THE ANTIBIOTIC YA-56 COMPLEX: TAXONOMY AND PRODUCTION OF THE PRODUCING STRAIN
A new complex of phleomycin-bleomycin group antibiotics, YA-56, was isolated from the culture broth of a streptomycete designated as strain MCRL 0387 and identified as a new variety of Streptomyces humidus NAKAZAWA and SHIBATA in IMAMURA et al., 1956. Ultra-violet irradiation of strain MCRL 0387 gav...
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| Veröffentlicht in: | Journal of antibiotics 1973, Vol.26(2), pp.70-76 |
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| container_end_page | 76 |
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| container_issue | 2 |
| container_start_page | 70 |
| container_title | Journal of antibiotics |
| container_volume | 26 |
| creator | FURUMAI, TAMOTSU TAKEDA, KATSUO TANI, KATO MATSUZAWA, NOBUO SHIMIZU, YOJI OHASHI, YOSHITAMI OKUDA, TOMOHARU |
| description | A new complex of phleomycin-bleomycin group antibiotics, YA-56, was isolated from the culture broth of a streptomycete designated as strain MCRL 0387 and identified as a new variety of Streptomyces humidus NAKAZAWA and SHIBATA in IMAMURA et al., 1956. Ultra-violet irradiation of strain MCRL 0387 gave a high-yielding mutant which formed blue aerial mycelium instead of the grayish aerial mycelium of the original strain. Fermentative production of the antibiotics YA-56 complex is described. |
| doi_str_mv | 10.7164/antibiotics.26.70 |
| format | Article |
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Ultra-violet irradiation of strain MCRL 0387 gave a high-yielding mutant which formed blue aerial mycelium instead of the grayish aerial mycelium of the original strain. 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Antibiot.</addtitle><description>A new complex of phleomycin-bleomycin group antibiotics, YA-56, was isolated from the culture broth of a streptomycete designated as strain MCRL 0387 and identified as a new variety of Streptomyces humidus NAKAZAWA and SHIBATA in IMAMURA et al., 1956. Ultra-violet irradiation of strain MCRL 0387 gave a high-yielding mutant which formed blue aerial mycelium instead of the grayish aerial mycelium of the original strain. Fermentative production of the antibiotics YA-56 complex is described.</description><subject>Anti-Bacterial Agents - biosynthesis</subject><subject>Bleomycin</subject><subject>Carbon - metabolism</subject><subject>Fermentation</subject><subject>Glycosides - biosynthesis</subject><subject>Microscopy, Electron</subject><subject>Mutation</subject><subject>Radiation Effects</subject><subject>Streptomyces - classification</subject><subject>Streptomyces - metabolism</subject><subject>Streptomyces - radiation effects</subject><subject>Ultraviolet Rays</subject><issn>0021-8820</issn><issn>1881-1469</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkF9PwjAUxRujQUQ_gA8m_QLD3q5rO9_m-DcDK8GRwNNSuk5HQMg2H_z2jowQXu5N7jnnl5uD0DOQvgDOXvVPXWyKQ12Yqk95X5Ab1AUpwQHG_VvUJYSCIyUl9-ihqraEuMIVsoM6DFwATrpolkyGOIiT6D1SSRTideB4HIdqNp8OV284CVYqVrN1Yxng-UINlmESqRirET4F20sUj_Fnsgii-BHd5XpX2afz7qHlaJiEE2eqxlEYTB3jUa92uGdyIHkOnErCpWDGus03dJP5xGeZEMbzDbfC00x7DLif-VJLAwBUGiqk20PQck15qKrS5umxLPa6_EuBpKdm0qtmUspTQZrMS5s5_m72NrskzlU0-kerb6taf9mLrssGsrPXRPC5PFFpOwS5mMy3LlP74_4DIiB0-Q</recordid><startdate>19730101</startdate><enddate>19730101</enddate><creator>FURUMAI, TAMOTSU</creator><creator>TAKEDA, KATSUO</creator><creator>TANI, KATO</creator><creator>MATSUZAWA, NOBUO</creator><creator>SHIMIZU, YOJI</creator><creator>OHASHI, YOSHITAMI</creator><creator>OKUDA, TOMOHARU</creator><general>JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19730101</creationdate><title>THE ANTIBIOTIC YA-56 COMPLEX: TAXONOMY AND PRODUCTION OF THE PRODUCING STRAIN</title><author>FURUMAI, TAMOTSU ; TAKEDA, KATSUO ; TANI, KATO ; MATSUZAWA, NOBUO ; SHIMIZU, YOJI ; OHASHI, YOSHITAMI ; OKUDA, TOMOHARU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-65cf10ff162806874ce31602bd9094d77c59c6e75a4a54169d98a8c11128c2783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Anti-Bacterial Agents - biosynthesis</topic><topic>Bleomycin</topic><topic>Carbon - metabolism</topic><topic>Fermentation</topic><topic>Glycosides - biosynthesis</topic><topic>Microscopy, Electron</topic><topic>Mutation</topic><topic>Radiation Effects</topic><topic>Streptomyces - classification</topic><topic>Streptomyces - metabolism</topic><topic>Streptomyces - radiation effects</topic><topic>Ultraviolet Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FURUMAI, TAMOTSU</creatorcontrib><creatorcontrib>TAKEDA, KATSUO</creatorcontrib><creatorcontrib>TANI, KATO</creatorcontrib><creatorcontrib>MATSUZAWA, NOBUO</creatorcontrib><creatorcontrib>SHIMIZU, YOJI</creatorcontrib><creatorcontrib>OHASHI, YOSHITAMI</creatorcontrib><creatorcontrib>OKUDA, TOMOHARU</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of antibiotics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FURUMAI, TAMOTSU</au><au>TAKEDA, KATSUO</au><au>TANI, KATO</au><au>MATSUZAWA, NOBUO</au><au>SHIMIZU, YOJI</au><au>OHASHI, YOSHITAMI</au><au>OKUDA, TOMOHARU</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THE ANTIBIOTIC YA-56 COMPLEX: TAXONOMY AND PRODUCTION OF THE PRODUCING STRAIN</atitle><jtitle>Journal of antibiotics</jtitle><addtitle>J. Antibiot.</addtitle><date>1973-01-01</date><risdate>1973</risdate><volume>26</volume><issue>2</issue><spage>70</spage><epage>76</epage><pages>70-76</pages><issn>0021-8820</issn><eissn>1881-1469</eissn><abstract>A new complex of phleomycin-bleomycin group antibiotics, YA-56, was isolated from the culture broth of a streptomycete designated as strain MCRL 0387 and identified as a new variety of Streptomyces humidus NAKAZAWA and SHIBATA in IMAMURA et al., 1956. Ultra-violet irradiation of strain MCRL 0387 gave a high-yielding mutant which formed blue aerial mycelium instead of the grayish aerial mycelium of the original strain. Fermentative production of the antibiotics YA-56 complex is described.</abstract><cop>Japan</cop><pub>JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</pub><pmid>4131160</pmid><doi>10.7164/antibiotics.26.70</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0021-8820 |
| ispartof | The Journal of Antibiotics, 1973, Vol.26(2), pp.70-76 |
| issn | 0021-8820 1881-1469 |
| language | eng |
| recordid | cdi_crossref_primary_10_7164_antibiotics_26_70 |
| source | J-STAGE Free; MEDLINE |
| subjects | Anti-Bacterial Agents - biosynthesis Bleomycin Carbon - metabolism Fermentation Glycosides - biosynthesis Microscopy, Electron Mutation Radiation Effects Streptomyces - classification Streptomyces - metabolism Streptomyces - radiation effects Ultraviolet Rays |
| title | THE ANTIBIOTIC YA-56 COMPLEX: TAXONOMY AND PRODUCTION OF THE PRODUCING STRAIN |
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