IN VITRO EFFECT OF ISOSCHAFTOSIDE ISOLATED FROM Syngonium podophyllum ON PIG KIDNEY Na + , K + -ATPASE
The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significant...
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| Veröffentlicht in: | Química Nova 2014, Vol.37 (10), p.1606-1609 |
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| creator | Gomes, Anne Caroline Candido Sampaio, Luzia da Silva Silva, Paulo André da Lamas, Marcelo Einicker Sakuragui, Cassia Mônica Barreto Junior, Cleber Bomfim Simas, Naomi Kato Kuster, Ricardo Machado |
| description | The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension. |
| doi_str_mv | 10.5935/0100-4042.20140257 |
| format | Article |
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Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.</description><subject>Araceae</subject><subject>CHEMISTRY, MULTIDISCIPLINARY</subject><subject>enzyme inhibition</subject><subject>Isoschaftoside</subject><subject>renal Na+, K+-ATPase</subject><subject>Syngonium podophyllum</subject><issn>0100-4042</issn><issn>1678-7064</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNo9UU1vgkAQ5dAmtbZ_oKe9t9j9ZPVIEJRowQht0tNmd2EtBl0DevDfF7R1DjPzJnkvL28c5wXBEZsQ9g4RhC6FFI8wRBRixu-cwe344Dy27RZCzAlnA8fECfiK83UKwigKgxykEYizNAvmfpSnWTwNe7j083AKonX6AbLzfmP31WkHDrawh59zXXd7moBVPAOLeJqE3yCR4BW8gUXXXT9f-Vn45NwbWbfl898cOp9RmAdzd5nO4sBfupowfHSxYWTMJC4QZZSU2uOKIYgMN4XWSHWmFTKe1oZzpUkhIaNQUcaU9KD2oCJDJ77qFlZuxaGpdrI5CysrcTnYZiNkc6x0XYoSmYJBrsYUl9SMywmnivMJJcpDRYEnndboqtXqqqyt2NpTs-_Mi6wPU_RhXgLuUVdeR8BXgm5s2zaluRlAUPSvETei-H8N-QU1LXh9</recordid><startdate>2014</startdate><enddate>2014</enddate><creator>Gomes, Anne Caroline Candido</creator><creator>Sampaio, Luzia da Silva</creator><creator>Silva, Paulo André da</creator><creator>Lamas, Marcelo Einicker</creator><creator>Sakuragui, Cassia Mônica</creator><creator>Barreto Junior, Cleber Bomfim</creator><creator>Simas, Naomi Kato</creator><creator>Kuster, Ricardo Machado</creator><general>Sociedade Brasileira de Química</general><scope>AAYXX</scope><scope>CITATION</scope><scope>GPN</scope><scope>DOA</scope></search><sort><creationdate>2014</creationdate><title>IN VITRO EFFECT OF ISOSCHAFTOSIDE ISOLATED FROM Syngonium podophyllum ON PIG KIDNEY Na + , K + -ATPASE</title><author>Gomes, Anne Caroline Candido ; Sampaio, Luzia da Silva ; Silva, Paulo André da ; Lamas, Marcelo Einicker ; Sakuragui, Cassia Mônica ; Barreto Junior, Cleber Bomfim ; Simas, Naomi Kato ; Kuster, Ricardo Machado</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-2f5385a2d14543ec67b5101f7fdcc1b027b1f6ccf77bc3da0540b455ba60c60b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Araceae</topic><topic>CHEMISTRY, MULTIDISCIPLINARY</topic><topic>enzyme inhibition</topic><topic>Isoschaftoside</topic><topic>renal Na+, K+-ATPase</topic><topic>Syngonium podophyllum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gomes, Anne Caroline Candido</creatorcontrib><creatorcontrib>Sampaio, Luzia da Silva</creatorcontrib><creatorcontrib>Silva, Paulo André da</creatorcontrib><creatorcontrib>Lamas, Marcelo Einicker</creatorcontrib><creatorcontrib>Sakuragui, Cassia Mônica</creatorcontrib><creatorcontrib>Barreto Junior, Cleber Bomfim</creatorcontrib><creatorcontrib>Simas, Naomi Kato</creatorcontrib><creatorcontrib>Kuster, Ricardo Machado</creatorcontrib><collection>CrossRef</collection><collection>SciELO</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Química Nova</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gomes, Anne Caroline Candido</au><au>Sampaio, Luzia da Silva</au><au>Silva, Paulo André da</au><au>Lamas, Marcelo Einicker</au><au>Sakuragui, Cassia Mônica</au><au>Barreto Junior, Cleber Bomfim</au><au>Simas, Naomi Kato</au><au>Kuster, Ricardo Machado</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IN VITRO EFFECT OF ISOSCHAFTOSIDE ISOLATED FROM Syngonium podophyllum ON PIG KIDNEY Na + , K + -ATPASE</atitle><jtitle>Química Nova</jtitle><addtitle>Quím. Nova</addtitle><date>2014</date><risdate>2014</risdate><volume>37</volume><issue>10</issue><spage>1606</spage><epage>1609</epage><pages>1606-1609</pages><issn>0100-4042</issn><issn>1678-7064</issn><abstract>The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.</abstract><pub>Sociedade Brasileira de Química</pub><doi>10.5935/0100-4042.20140257</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry |
| subjects | Araceae CHEMISTRY, MULTIDISCIPLINARY enzyme inhibition Isoschaftoside renal Na+, K+-ATPase Syngonium podophyllum |
| title | IN VITRO EFFECT OF ISOSCHAFTOSIDE ISOLATED FROM Syngonium podophyllum ON PIG KIDNEY Na + , K + -ATPASE |
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