Clinical Evaluation of Thymidine Phosphorylase Activity in Human Gastric Cancer with Special Reference to Metastatic Lymph Nodes and Relapsing Forms

To investigate the expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor (dThdPase/PD-ECGF) in gastric cancer, we measured its activity in normal tissues, cancer tissues and metastatic lymph nodes of 75 patients with resected advanced gastric cancer, and compared the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nippon Shokaki Geka Gakkai zasshi 1999, Vol.32(10), pp.2325-2332
Hauptverfasser:	Yabusaki, Hiroshi, Nashimoto, Atsushi, Tsuchiya, Yoshiaki, Tsutsui, Mitsuhiro, Tanaka, Otsuo, Sasaki, Juei
Format:	Artikel
Sprache:	jpn
Schlagworte:	gastric cancer immunohistochemical study lymph node metastasis of gastric cancer relapsing forms of gastric cancer thymidine phosphorylase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	To investigate the expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor (dThdPase/PD-ECGF) in gastric cancer, we measured its activity in normal tissues, cancer tissues and metastatic lymph nodes of 75 patients with resected advanced gastric cancer, and compared the results with histopathological features. We also evaluated cancer tissues immunohistochemically using anti-dThdPase antibody. The dThdPase activity was significantly higher in metastatic lymph nodes than in normal tissues (p
ISSN:	0386-9768 1348-9372
DOI:	10.5833/jjgs.32.2325