Disorders of sexual development: a case of XX sex reversal in a mixed breed dog negative for SRY (sex-determining region on the Y chromosome) gene

An 8-month mixed breed dog (from shelter) was evaluated for its abnormal external genital (enlarged os clitoris protruding externally from the vulva) condition. Dog had phenotypic female appearance. Testicular-like tissue was removed via laparoscopy-assisted gonadectomy. Genotype was determined usin...

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Veröffentlicht in:Clinical theriogenology 2022-06, Vol.14 (2), p.110-114
Hauptverfasser: Martin, Kelsey, Parsons, Agata, Burns, Greg, Bouma, Gerrit, Hollinshead, Fiona
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container_end_page 114
container_issue 2
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container_title Clinical theriogenology
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creator Martin, Kelsey
Parsons, Agata
Burns, Greg
Bouma, Gerrit
Hollinshead, Fiona
description An 8-month mixed breed dog (from shelter) was evaluated for its abnormal external genital (enlarged os clitoris protruding externally from the vulva) condition. Dog had phenotypic female appearance. Testicular-like tissue was removed via laparoscopy-assisted gonadectomy. Genotype was determined using blood and gonadal tissue (via histology and immunohistochemistry). Dog had XX chromosomes and was negative for SRY (sex-determining region on the Y chromosome) gene.
doi_str_mv 10.58292/ct.v14.9141
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title Disorders of sexual development: a case of XX sex reversal in a mixed breed dog negative for SRY (sex-determining region on the Y chromosome) gene
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