Hormone receptor analysis for breast cancer in cell-block preparation

Hormone receptor analysis for breast cancer in cell-block preparation

Objective : Several studies have shown receptor discrepancies between primary tumors and metastases. In metastatic diagnosis, cell-block cytology (CBC) is superior to liquid-based cytology (LBC) due to the easy addition of special staining and low cost. We compare the usefulness of CBC versus LBC in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nippon Rinsho Saibo Gakkai zasshi 2012, Vol.51(5), pp.323-328
Hauptverfasser: NISHIMURA, Rieko, YAMAMOTO, Tamami, KAGAWA, Akihiro, MORITA, Sachiko, TERAMOTO, Norihiro, TAKAHATA, Hiroyuki
Format: Artikel
Sprache:eng ; jpn
Schlagworte:
Breast cancer
Cell-block
Cytology
Hormone receptor
Liquid-based cytology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 328
container_issue 5
container_start_page 323
container_title Nippon Rinsho Saibo Gakkai zasshi
container_volume 51
creator NISHIMURA, Rieko
YAMAMOTO, Tamami
KAGAWA, Akihiro
MORITA, Sachiko
TERAMOTO, Norihiro
TAKAHATA, Hiroyuki
description Objective : Several studies have shown receptor discrepancies between primary tumors and metastases. In metastatic diagnosis, cell-block cytology (CBC) is superior to liquid-based cytology (LBC) due to the easy addition of special staining and low cost. We compare the usefulness of CBC versus LBC in hormone receptor (HR) analysis. Study Design : Specimens aspirated from surgically resected breast tissue prepared for CBC and LBC were immunostained for HRs and HR results compared to those for surgical specimens and LBC. Results : HR results for CBC agreed with those of histology in 34 of 35 cases, with a concordance rate of 97% for the estrogen receptor and in 31 of 35 cases, with a concordance rate of 89% for the progesterone receptor. Overall HR concordance rate for the CBC and histology was 97% in 34 of 35 cases. HR results for CBC agreed with those of LBC in all cases for overall HR. Conclusion : In HR breast cancer analysis, CBC results correlated well with the LBC results and histology specimens.
doi_str_mv 10.5795/jjscc.51.323
format Article
fullrecord <record><control><sourceid>jstage_cross</sourceid><recordid>TN_cdi_crossref_primary_10_5795_jjscc_51_323</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>article_jjscc_51_5_51_323_article_char_en</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1883-4885793925aa379203621dfe0a35fab91ad5070dde042a922f7addd05b92ea313</originalsourceid><addsrcrecordid>eNpFkMFOwzAMhiMEEtPYjQfIA9CRxMvanBCaBkOaxAXOkZu40NG1ldPL3p7Cpu1kWf5-69cnxL1Wc5s7-7jbpRDmVs_BwJWY6KIwWW4ArsVEQZFnWju4FbOU6lIZ0Es1AhOx3nS871qSTIH6oWOJLTaHVCdZjUvJhGmQAdtALOtWBmqarGy68CN7ph4Zh7pr78RNhU2i2WlOxefL-mO1ybbvr2-r520WxjqQLYpirArOWETInVGwNDpWpBBshaXTGK3KVYykFgadMVWOMUZlS2cIQcNUPBz_Bu5SYqp8z_Ue-eC18n8W_L8Fb7UfLYz40xHfpQG_6AwjD3Vo6ALbU-J8Cd_Inlr4BSQeaBo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Hormone receptor analysis for breast cancer in cell-block preparation</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>NISHIMURA, Rieko ; YAMAMOTO, Tamami ; KAGAWA, Akihiro ; MORITA, Sachiko ; TERAMOTO, Norihiro ; TAKAHATA, Hiroyuki</creator><creatorcontrib>NISHIMURA, Rieko ; YAMAMOTO, Tamami ; KAGAWA, Akihiro ; MORITA, Sachiko ; TERAMOTO, Norihiro ; TAKAHATA, Hiroyuki</creatorcontrib><description>Objective : Several studies have shown receptor discrepancies between primary tumors and metastases. In metastatic diagnosis, cell-block cytology (CBC) is superior to liquid-based cytology (LBC) due to the easy addition of special staining and low cost. We compare the usefulness of CBC versus LBC in hormone receptor (HR) analysis. Study Design : Specimens aspirated from surgically resected breast tissue prepared for CBC and LBC were immunostained for HRs and HR results compared to those for surgical specimens and LBC. Results : HR results for CBC agreed with those of histology in 34 of 35 cases, with a concordance rate of 97% for the estrogen receptor and in 31 of 35 cases, with a concordance rate of 89% for the progesterone receptor. Overall HR concordance rate for the CBC and histology was 97% in 34 of 35 cases. HR results for CBC agreed with those of LBC in all cases for overall HR. Conclusion : In HR breast cancer analysis, CBC results correlated well with the LBC results and histology specimens.</description><identifier>ISSN: 0387-1193</identifier><identifier>EISSN: 1882-7233</identifier><identifier>DOI: 10.5795/jjscc.51.323</identifier><language>eng ; jpn</language><publisher>The Japanese Society of Clinical Cytology</publisher><subject>Breast cancer ; Cell-block ; Cytology ; Hormone receptor ; Liquid-based cytology</subject><ispartof>The Journal of the Japanese Society of Clinical Cytology, 2012, Vol.51(5), pp.323-328</ispartof><rights>2012 The Japanese Society of Clinical Cytology</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1883-4885793925aa379203621dfe0a35fab91ad5070dde042a922f7addd05b92ea313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,4025,27928,27929,27930</link.rule.ids></links><search><creatorcontrib>NISHIMURA, Rieko</creatorcontrib><creatorcontrib>YAMAMOTO, Tamami</creatorcontrib><creatorcontrib>KAGAWA, Akihiro</creatorcontrib><creatorcontrib>MORITA, Sachiko</creatorcontrib><creatorcontrib>TERAMOTO, Norihiro</creatorcontrib><creatorcontrib>TAKAHATA, Hiroyuki</creatorcontrib><title>Hormone receptor analysis for breast cancer in cell-block preparation</title><title>Nippon Rinsho Saibo Gakkai zasshi</title><addtitle>J. Jpn. Soc. Clin. Cytol.</addtitle><description>Objective : Several studies have shown receptor discrepancies between primary tumors and metastases. In metastatic diagnosis, cell-block cytology (CBC) is superior to liquid-based cytology (LBC) due to the easy addition of special staining and low cost. We compare the usefulness of CBC versus LBC in hormone receptor (HR) analysis. Study Design : Specimens aspirated from surgically resected breast tissue prepared for CBC and LBC were immunostained for HRs and HR results compared to those for surgical specimens and LBC. Results : HR results for CBC agreed with those of histology in 34 of 35 cases, with a concordance rate of 97% for the estrogen receptor and in 31 of 35 cases, with a concordance rate of 89% for the progesterone receptor. Overall HR concordance rate for the CBC and histology was 97% in 34 of 35 cases. HR results for CBC agreed with those of LBC in all cases for overall HR. Conclusion : In HR breast cancer analysis, CBC results correlated well with the LBC results and histology specimens.</description><subject>Breast cancer</subject><subject>Cell-block</subject><subject>Cytology</subject><subject>Hormone receptor</subject><subject>Liquid-based cytology</subject><issn>0387-1193</issn><issn>1882-7233</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNpFkMFOwzAMhiMEEtPYjQfIA9CRxMvanBCaBkOaxAXOkZu40NG1ldPL3p7Cpu1kWf5-69cnxL1Wc5s7-7jbpRDmVs_BwJWY6KIwWW4ArsVEQZFnWju4FbOU6lIZ0Es1AhOx3nS871qSTIH6oWOJLTaHVCdZjUvJhGmQAdtALOtWBmqarGy68CN7ph4Zh7pr78RNhU2i2WlOxefL-mO1ybbvr2-r520WxjqQLYpirArOWETInVGwNDpWpBBshaXTGK3KVYykFgadMVWOMUZlS2cIQcNUPBz_Bu5SYqp8z_Ue-eC18n8W_L8Fb7UfLYz40xHfpQG_6AwjD3Vo6ALbU-J8Cd_Inlr4BSQeaBo</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>NISHIMURA, Rieko</creator><creator>YAMAMOTO, Tamami</creator><creator>KAGAWA, Akihiro</creator><creator>MORITA, Sachiko</creator><creator>TERAMOTO, Norihiro</creator><creator>TAKAHATA, Hiroyuki</creator><general>The Japanese Society of Clinical Cytology</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2012</creationdate><title>Hormone receptor analysis for breast cancer in cell-block preparation</title><author>NISHIMURA, Rieko ; YAMAMOTO, Tamami ; KAGAWA, Akihiro ; MORITA, Sachiko ; TERAMOTO, Norihiro ; TAKAHATA, Hiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1883-4885793925aa379203621dfe0a35fab91ad5070dde042a922f7addd05b92ea313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>2012</creationdate><topic>Breast cancer</topic><topic>Cell-block</topic><topic>Cytology</topic><topic>Hormone receptor</topic><topic>Liquid-based cytology</topic><toplevel>online_resources</toplevel><creatorcontrib>NISHIMURA, Rieko</creatorcontrib><creatorcontrib>YAMAMOTO, Tamami</creatorcontrib><creatorcontrib>KAGAWA, Akihiro</creatorcontrib><creatorcontrib>MORITA, Sachiko</creatorcontrib><creatorcontrib>TERAMOTO, Norihiro</creatorcontrib><creatorcontrib>TAKAHATA, Hiroyuki</creatorcontrib><collection>CrossRef</collection><jtitle>Nippon Rinsho Saibo Gakkai zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NISHIMURA, Rieko</au><au>YAMAMOTO, Tamami</au><au>KAGAWA, Akihiro</au><au>MORITA, Sachiko</au><au>TERAMOTO, Norihiro</au><au>TAKAHATA, Hiroyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hormone receptor analysis for breast cancer in cell-block preparation</atitle><jtitle>Nippon Rinsho Saibo Gakkai zasshi</jtitle><addtitle>J. Jpn. Soc. Clin. Cytol.</addtitle><date>2012</date><risdate>2012</risdate><volume>51</volume><issue>5</issue><spage>323</spage><epage>328</epage><pages>323-328</pages><issn>0387-1193</issn><eissn>1882-7233</eissn><abstract>Objective : Several studies have shown receptor discrepancies between primary tumors and metastases. In metastatic diagnosis, cell-block cytology (CBC) is superior to liquid-based cytology (LBC) due to the easy addition of special staining and low cost. We compare the usefulness of CBC versus LBC in hormone receptor (HR) analysis. Study Design : Specimens aspirated from surgically resected breast tissue prepared for CBC and LBC were immunostained for HRs and HR results compared to those for surgical specimens and LBC. Results : HR results for CBC agreed with those of histology in 34 of 35 cases, with a concordance rate of 97% for the estrogen receptor and in 31 of 35 cases, with a concordance rate of 89% for the progesterone receptor. Overall HR concordance rate for the CBC and histology was 97% in 34 of 35 cases. HR results for CBC agreed with those of LBC in all cases for overall HR. Conclusion : In HR breast cancer analysis, CBC results correlated well with the LBC results and histology specimens.</abstract><pub>The Japanese Society of Clinical Cytology</pub><doi>10.5795/jjscc.51.323</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0387-1193
ispartof The Journal of the Japanese Society of Clinical Cytology, 2012, Vol.51(5), pp.323-328
issn 0387-1193
1882-7233
language eng ; jpn
recordid cdi_crossref_primary_10_5795_jjscc_51_323
source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Breast cancer
Cell-block
Cytology
Hormone receptor
Liquid-based cytology
title Hormone receptor analysis for breast cancer in cell-block preparation
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T21%3A45%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstage_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hormone%20receptor%20analysis%20for%20breast%20cancer%20in%20cell-block%20preparation&rft.jtitle=Nippon%20Rinsho%20Saibo%20Gakkai%20zasshi&rft.au=NISHIMURA,%20Rieko&rft.date=2012&rft.volume=51&rft.issue=5&rft.spage=323&rft.epage=328&rft.pages=323-328&rft.issn=0387-1193&rft.eissn=1882-7233&rft_id=info:doi/10.5795/jjscc.51.323&rft_dat=%3Cjstage_cross%3Earticle_jjscc_51_5_51_323_article_char_en%3C/jstage_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true