Nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology: A case report

Background : Nodular fasciitis is a benign disease characterized by reactive fibroblast proliferation and is also called pseudosarcomatous fibromatosis. Differentiation of nodular fasciitis from sarcoma is difficult. We report a rare case of estrogen receptor (ER)-positive nodular fasciitis of the b...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nippon Rinsho Saibo Gakkai zasshi 2008, Vol.47(2), pp.137-141
Hauptverfasser: MAEDA, Shotaro, KATAYAMA, Hironori, MASUDA, Yumi, IWASE, Hiromi, NAITO, Zenya, YOKOYAMA, Tadashi, FURUKAWA, Kiyonori, TAJIRI, Takashi
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 141
container_issue 2
container_start_page 137
container_title Nippon Rinsho Saibo Gakkai zasshi
container_volume 47
creator MAEDA, Shotaro
KATAYAMA, Hironori
MASUDA, Yumi
IWASE, Hiromi
NAITO, Zenya
YOKOYAMA, Tadashi
FURUKAWA, Kiyonori
TAJIRI, Takashi
description Background : Nodular fasciitis is a benign disease characterized by reactive fibroblast proliferation and is also called pseudosarcomatous fibromatosis. Differentiation of nodular fasciitis from sarcoma is difficult. We report a rare case of estrogen receptor (ER)-positive nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology (FNAC). Case : A 35-year-old woman presented with a 2×1×1.5 cm palpable, nonfixed nodule in the upper outer quadrant of the right breast. FNAC revealed the presence of many uniformly fusiform fibroblasts containing spherical and oval nuclei with inflammatory cells and myxoid substance in the background. On the basis of these findings, we made a diagnosis of nodular fasciitis (Class II). Core needle biopsy revealed numerous fibroblasts forming a “tissue culture-like” appearance, and inflammatory cells and interstitial myxoid substance ; findings that supported the diagnosis of nodular fasciitis. The nodule was suspected of being malignant clinically, and excisional biopsy was performed. The nodule proximal to the fascia was definitely diagnosed as ER-positive nodular fasciitis. Conclusion : We encountered a rare case of ER-positive nodular fasciitis that developed in the breast, and we diagnosed it as a nodular fasciitis based on the FNAC findings alone. The possibility of nodular fasciitis should always be kept in mind when performing FNAC of breast tumors.
doi_str_mv 10.5795/jjscc.47.137
format Article
fullrecord <record><control><sourceid>jstage_cross</sourceid><recordid>TN_cdi_crossref_primary_10_5795_jjscc_47_137</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>article_jjscc_47_2_47_2_137_article_char_en</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2667-14fa687643adee2352e6fd8c960a3186c9ba6c0b5202a6d96e702b4cefd4f6df3</originalsourceid><addsrcrecordid>eNpFkMtOwzAQRS0EEqWw4wP8AaQ4tmPHy6riJVWwgXU0sceto5BUtlnk7wkUlc3MYs5cXR1Cbku2qrSp7rsuWbuSelUKfUYWZV3zQnMhzsmCiVoXZWnEJblKqWNMScPMgmxfR_fVQ6Qekg0hh0RHT_MeaRsRUqYuwG4YEzraTtSHAYsB0fVIIR1ChBzGgdopj_24m67JhYc-4c3fXpKPx4f3zXOxfXt62ay3heVKzTWkB1VrJQU4RC4qjsq72hrFQJS1sqYFZVlbccZBOaNQM95Ki95Jr5wXS3J3zLVxTCmibw4xfEKcmpI1PyaaXxON1M1sYsbXR7xLGXZ4giHmYHv8h_lxzD-nm91DbHAQ38Zla3s</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology: A case report</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>MAEDA, Shotaro ; KATAYAMA, Hironori ; MASUDA, Yumi ; IWASE, Hiromi ; NAITO, Zenya ; YOKOYAMA, Tadashi ; FURUKAWA, Kiyonori ; TAJIRI, Takashi</creator><creatorcontrib>MAEDA, Shotaro ; KATAYAMA, Hironori ; MASUDA, Yumi ; IWASE, Hiromi ; NAITO, Zenya ; YOKOYAMA, Tadashi ; FURUKAWA, Kiyonori ; TAJIRI, Takashi</creatorcontrib><description>Background : Nodular fasciitis is a benign disease characterized by reactive fibroblast proliferation and is also called pseudosarcomatous fibromatosis. Differentiation of nodular fasciitis from sarcoma is difficult. We report a rare case of estrogen receptor (ER)-positive nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology (FNAC). Case : A 35-year-old woman presented with a 2×1×1.5 cm palpable, nonfixed nodule in the upper outer quadrant of the right breast. FNAC revealed the presence of many uniformly fusiform fibroblasts containing spherical and oval nuclei with inflammatory cells and myxoid substance in the background. On the basis of these findings, we made a diagnosis of nodular fasciitis (Class II). Core needle biopsy revealed numerous fibroblasts forming a “tissue culture-like” appearance, and inflammatory cells and interstitial myxoid substance ; findings that supported the diagnosis of nodular fasciitis. The nodule was suspected of being malignant clinically, and excisional biopsy was performed. The nodule proximal to the fascia was definitely diagnosed as ER-positive nodular fasciitis. Conclusion : We encountered a rare case of ER-positive nodular fasciitis that developed in the breast, and we diagnosed it as a nodular fasciitis based on the FNAC findings alone. The possibility of nodular fasciitis should always be kept in mind when performing FNAC of breast tumors.</description><identifier>ISSN: 0387-1193</identifier><identifier>EISSN: 1882-7233</identifier><identifier>DOI: 10.5795/jjscc.47.137</identifier><language>eng</language><publisher>The Japanese Society of Clinical Cytology</publisher><subject>Breast ; Estrogen receptor (ER) ; Fine-needle aspiration cytology (FNAC) ; Nodular fasciitis</subject><ispartof>The Journal of the Japanese Society of Clinical Cytology, 2008, Vol.47(2), pp.137-141</ispartof><rights>2008 The Japanese Society of Clinical Cytology</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2667-14fa687643adee2352e6fd8c960a3186c9ba6c0b5202a6d96e702b4cefd4f6df3</citedby><cites>FETCH-LOGICAL-c2667-14fa687643adee2352e6fd8c960a3186c9ba6c0b5202a6d96e702b4cefd4f6df3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4009,27902,27903,27904</link.rule.ids></links><search><creatorcontrib>MAEDA, Shotaro</creatorcontrib><creatorcontrib>KATAYAMA, Hironori</creatorcontrib><creatorcontrib>MASUDA, Yumi</creatorcontrib><creatorcontrib>IWASE, Hiromi</creatorcontrib><creatorcontrib>NAITO, Zenya</creatorcontrib><creatorcontrib>YOKOYAMA, Tadashi</creatorcontrib><creatorcontrib>FURUKAWA, Kiyonori</creatorcontrib><creatorcontrib>TAJIRI, Takashi</creatorcontrib><title>Nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology: A case report</title><title>Nippon Rinsho Saibo Gakkai zasshi</title><addtitle>J. Jpn. Soc. Clin. Cytol.</addtitle><description>Background : Nodular fasciitis is a benign disease characterized by reactive fibroblast proliferation and is also called pseudosarcomatous fibromatosis. Differentiation of nodular fasciitis from sarcoma is difficult. We report a rare case of estrogen receptor (ER)-positive nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology (FNAC). Case : A 35-year-old woman presented with a 2×1×1.5 cm palpable, nonfixed nodule in the upper outer quadrant of the right breast. FNAC revealed the presence of many uniformly fusiform fibroblasts containing spherical and oval nuclei with inflammatory cells and myxoid substance in the background. On the basis of these findings, we made a diagnosis of nodular fasciitis (Class II). Core needle biopsy revealed numerous fibroblasts forming a “tissue culture-like” appearance, and inflammatory cells and interstitial myxoid substance ; findings that supported the diagnosis of nodular fasciitis. The nodule was suspected of being malignant clinically, and excisional biopsy was performed. The nodule proximal to the fascia was definitely diagnosed as ER-positive nodular fasciitis. Conclusion : We encountered a rare case of ER-positive nodular fasciitis that developed in the breast, and we diagnosed it as a nodular fasciitis based on the FNAC findings alone. The possibility of nodular fasciitis should always be kept in mind when performing FNAC of breast tumors.</description><subject>Breast</subject><subject>Estrogen receptor (ER)</subject><subject>Fine-needle aspiration cytology (FNAC)</subject><subject>Nodular fasciitis</subject><issn>0387-1193</issn><issn>1882-7233</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNpFkMtOwzAQRS0EEqWw4wP8AaQ4tmPHy6riJVWwgXU0sceto5BUtlnk7wkUlc3MYs5cXR1Cbku2qrSp7rsuWbuSelUKfUYWZV3zQnMhzsmCiVoXZWnEJblKqWNMScPMgmxfR_fVQ6Qekg0hh0RHT_MeaRsRUqYuwG4YEzraTtSHAYsB0fVIIR1ChBzGgdopj_24m67JhYc-4c3fXpKPx4f3zXOxfXt62ay3heVKzTWkB1VrJQU4RC4qjsq72hrFQJS1sqYFZVlbccZBOaNQM95Ki95Jr5wXS3J3zLVxTCmibw4xfEKcmpI1PyaaXxON1M1sYsbXR7xLGXZ4giHmYHv8h_lxzD-nm91DbHAQ38Zla3s</recordid><startdate>2008</startdate><enddate>2008</enddate><creator>MAEDA, Shotaro</creator><creator>KATAYAMA, Hironori</creator><creator>MASUDA, Yumi</creator><creator>IWASE, Hiromi</creator><creator>NAITO, Zenya</creator><creator>YOKOYAMA, Tadashi</creator><creator>FURUKAWA, Kiyonori</creator><creator>TAJIRI, Takashi</creator><general>The Japanese Society of Clinical Cytology</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2008</creationdate><title>Nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology</title><author>MAEDA, Shotaro ; KATAYAMA, Hironori ; MASUDA, Yumi ; IWASE, Hiromi ; NAITO, Zenya ; YOKOYAMA, Tadashi ; FURUKAWA, Kiyonori ; TAJIRI, Takashi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2667-14fa687643adee2352e6fd8c960a3186c9ba6c0b5202a6d96e702b4cefd4f6df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Breast</topic><topic>Estrogen receptor (ER)</topic><topic>Fine-needle aspiration cytology (FNAC)</topic><topic>Nodular fasciitis</topic><toplevel>online_resources</toplevel><creatorcontrib>MAEDA, Shotaro</creatorcontrib><creatorcontrib>KATAYAMA, Hironori</creatorcontrib><creatorcontrib>MASUDA, Yumi</creatorcontrib><creatorcontrib>IWASE, Hiromi</creatorcontrib><creatorcontrib>NAITO, Zenya</creatorcontrib><creatorcontrib>YOKOYAMA, Tadashi</creatorcontrib><creatorcontrib>FURUKAWA, Kiyonori</creatorcontrib><creatorcontrib>TAJIRI, Takashi</creatorcontrib><collection>CrossRef</collection><jtitle>Nippon Rinsho Saibo Gakkai zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MAEDA, Shotaro</au><au>KATAYAMA, Hironori</au><au>MASUDA, Yumi</au><au>IWASE, Hiromi</au><au>NAITO, Zenya</au><au>YOKOYAMA, Tadashi</au><au>FURUKAWA, Kiyonori</au><au>TAJIRI, Takashi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology: A case report</atitle><jtitle>Nippon Rinsho Saibo Gakkai zasshi</jtitle><addtitle>J. Jpn. Soc. Clin. Cytol.</addtitle><date>2008</date><risdate>2008</risdate><volume>47</volume><issue>2</issue><spage>137</spage><epage>141</epage><pages>137-141</pages><issn>0387-1193</issn><eissn>1882-7233</eissn><abstract>Background : Nodular fasciitis is a benign disease characterized by reactive fibroblast proliferation and is also called pseudosarcomatous fibromatosis. Differentiation of nodular fasciitis from sarcoma is difficult. We report a rare case of estrogen receptor (ER)-positive nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology (FNAC). Case : A 35-year-old woman presented with a 2×1×1.5 cm palpable, nonfixed nodule in the upper outer quadrant of the right breast. FNAC revealed the presence of many uniformly fusiform fibroblasts containing spherical and oval nuclei with inflammatory cells and myxoid substance in the background. On the basis of these findings, we made a diagnosis of nodular fasciitis (Class II). Core needle biopsy revealed numerous fibroblasts forming a “tissue culture-like” appearance, and inflammatory cells and interstitial myxoid substance ; findings that supported the diagnosis of nodular fasciitis. The nodule was suspected of being malignant clinically, and excisional biopsy was performed. The nodule proximal to the fascia was definitely diagnosed as ER-positive nodular fasciitis. Conclusion : We encountered a rare case of ER-positive nodular fasciitis that developed in the breast, and we diagnosed it as a nodular fasciitis based on the FNAC findings alone. The possibility of nodular fasciitis should always be kept in mind when performing FNAC of breast tumors.</abstract><pub>The Japanese Society of Clinical Cytology</pub><doi>10.5795/jjscc.47.137</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0387-1193
ispartof The Journal of the Japanese Society of Clinical Cytology, 2008, Vol.47(2), pp.137-141
issn 0387-1193
1882-7233
language eng
recordid cdi_crossref_primary_10_5795_jjscc_47_137
source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Breast
Estrogen receptor (ER)
Fine-needle aspiration cytology (FNAC)
Nodular fasciitis
title Nodular fasciitis of the breast diagnosed by fine-needle aspiration cytology: A case report
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T06%3A17%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstage_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Nodular%20fasciitis%20of%20the%20breast%20diagnosed%20by%20fine-needle%20aspiration%20cytology:%20A%20case%20report&rft.jtitle=Nippon%20Rinsho%20Saibo%20Gakkai%20zasshi&rft.au=MAEDA,%20Shotaro&rft.date=2008&rft.volume=47&rft.issue=2&rft.spage=137&rft.epage=141&rft.pages=137-141&rft.issn=0387-1193&rft.eissn=1882-7233&rft_id=info:doi/10.5795/jjscc.47.137&rft_dat=%3Cjstage_cross%3Earticle_jjscc_47_2_47_2_137_article_char_en%3C/jstage_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true