Cytological study of invasive thymoma and thymic carcinoma

We report the cytological characteristics of invasive thymoma and thymic carcinoma. First, left pleural effusion and an anterior mediastinal mass were found in a 62-year-old woman. Fine needle aspiration cytology showed cohesive clusters of epithelial cells and numerous scattered lymphocytes. Ellipt...

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Veröffentlicht in:Nippon Rinsho Saibo Gakkai zasshi 1995, Vol.34(6), pp.1104-1108
Hauptverfasser: HABA, Reiji, KOBAYASHI, Shoji, NOMA, Katuyuki, YANO, Yoshihito, OGAWA, Hiromiti, KUROKAWA, Tatuo, UMEDA, Masakiti
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container_end_page 1108
container_issue 6
container_start_page 1104
container_title Nippon Rinsho Saibo Gakkai zasshi
container_volume 34
creator HABA, Reiji
KOBAYASHI, Shoji
NOMA, Katuyuki
YANO, Yoshihito
OGAWA, Hiromiti
KUROKAWA, Tatuo
UMEDA, Masakiti
description We report the cytological characteristics of invasive thymoma and thymic carcinoma. First, left pleural effusion and an anterior mediastinal mass were found in a 62-year-old woman. Fine needle aspiration cytology showed cohesive clusters of epithelial cells and numerous scattered lymphocytes. Elliptical and polygonal tumor cells contained round and elliptical nuclei, fine aggregated chromatin and small nucleoli. The histological diagnosis was invasive thymoma. Next, an anterior mediastinal mass was found on medical examination. Metastatic liver cell tumors were detected by abdominal CT scan. Fine needle aspiration cytology showed scattered epithelial cells and lymphocytes. The nuclei were large and pleomorphic with coarsely granular chromatin and a few prominent nucleoli. The histological diagnosis was thymic carcinoma. Cytologically the differences between invasive thymoma and thymic carcinoma were pleomorphism of nuclei, increases in the N/C ratio and nuclear mitosis, coarsely granular chromatin and large nucleoli. It was difficult to determine the invasiveness of thymoma cytologically.
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subjects Case report
Cytology
Invasive thymoma
Thymic carcinoma
Thymus
title Cytological study of invasive thymoma and thymic carcinoma
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