Optical Resolution of Water-insoluble Intermediate of Diltiazem Hydrochloride by Lipase

Newly developed drugs have asymmetric atoms in their chemical structure, and biological effects reside ordinarily in only one of its enantiomers. Another enantiomer has different biological effects or toxicity. Their action on beings is competitive and differs in adsorption, metabolism, degradation...

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Veröffentlicht in:Journal of Japan Oil Chemists' Society 1995/10/20, Vol.44(10), pp.862-868
1. Verfasser: SHIBATANI, Takeji
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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