Determination of anamorelin concentration in human plasma using a simple high-performance liquid chromatography-ultraviolet detection method

Anamorelin, a non-peptide ghrelin analog and growth hormone secretagogue, is a novel oral drug used to treat cancer cachexia. Patients with cancer cachexia frequently use several drugs and anamorelin is a substrate of cytochrome P450 (CYP) 3A4; therefore, drug-drug interactions with CYP3A4 inhibitor...

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Veröffentlicht in:	Drug Discoveries & Therapeutics 2024/08/31, Vol.18(4), pp.260-264
Hauptverfasser:	Yasu, Takeo, Iwatuki, Nanami, Gando, Yoshito, Matumoto, Yasuhiko, Masuo, Masahiro, Shirota, Mikio, Kobayashi, Masayoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	cancer cachexia clinical settings drug-drug interactions
Online-Zugang:	Volltext
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