MgSO4 and lazaroid (U-83836E) partially protects glioma cells against glutamate toxicity in vitro

In this study, the possible effects of MgSO4 and lazaroid (U-83836E) on glutamate toxicity on glial cells were investigated. C6 and human glioblastoma multiforme cells derived from two patients were grown in an incubator. First, determined IC50 dose of L-glutamate (L-glu) was given for 24 hours and...

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Veröffentlicht in:	Acta neurobiologiae experimentalis 2004-01, Vol.64 (4), p.461-466
Hauptverfasser:	Kabadere, Selda, Oztopçu, Pinar, Korkmaz, Seval, Erol, Kevser, Uyar, Ruhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Calcium Channel Blockers - pharmacology Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Chromans - pharmacology Dose-Response Relationship, Drug Drug Interactions Glioma Glutamic Acid - pharmacology Humans Inhibitory Concentration 50 Magnesium Sulfate - pharmacology Mice Neuroglia - cytology Neuroglia - drug effects Piperazines - pharmacology Tetrazolium Salts Thiazoles
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