Leaky gut and inflammatory biomarkers in a medication overuse headache model in male rats

Medication overuse is common among chronic migraine patients and nonsteroidal antiinflammatory drugs (NSAIDs) are the most frequently overused drugs. The pathophysiological mechanisms underlying medication overuse headache (MOH) are not completely understood. Intestinal hyperpermeability and leaky g...

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Veröffentlicht in:	Turkish journal of medical sciences 2024, Vol.54 (1), p.33-41
Hauptverfasser:	Vuralli, Doğa, Dağidir, Hale Gök, Topa, Elif Abbasoğlu, Belen, Hayrunnisa Bolay
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute-Phase Proteins Animals Anti-Inflammatory Agents, Non-Steroidal Biomarkers - blood Brain - drug effects Brain - metabolism Carrier Proteins - blood Carrier Proteins - metabolism Disease Models, Animal Headache Disorders, Secondary - blood HMGB1 Protein - blood HMGB1 Protein - metabolism Inflammation - blood Inflammation - metabolism Interleukin-17 - blood Interleukin-17 - metabolism Interleukin-6 - blood Male Membrane Glycoproteins - blood Membrane Glycoproteins - metabolism Occludin - metabolism Rats Rats, Sprague-Dawley
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