In Vitro Activity of Biometal(II) Complexes of Monensin Against Virus-Induced Transplantable Animal Tumors

The anticancer properties of monensic acid (MonH) and its complexes with ions of Mg(II), Ca(II), Mn(II) and Co(II) were studied in cultured permanent cell lines originated from virus-induced transplantable tumors in chicken (hepatoma, LSCC-SF-Mc29) and in rat (sarcoma, LSR-SF-SR). The short-term exp...

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Veröffentlicht in:	Biotechnology, biotechnological equipment biotechnological equipment, 2013, Vol.27 (2), p.3703-3708
Hauptverfasser:	Pantcheva, Ivayla, Alexandrova, Radostina, Zhivkova, Tanya, Mitewa, Mariana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherent cells Anticancer properties Biotechnology Cell proliferation Coordination compounds cytotoxic/antiproliferative effects Cytotoxicity Hepatoma Magnesium Manganese Metal concentrations Monensin monensin biometal(II) complexes Poultry Sarcoma Time dependence Toxicity Tumor cell lines Tumor cells Tumors Virus-transformed chicken/rat tumor cells Viruses
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