Composite paraganglioma-ganglioneuroma of the urinary bladder: a rare neoplasm causing hemodynamic crisis at tumour resection

A 64-year-old man presented with gross painless hematuria.Cystoscopy revealed a submucosal bladder neck mass coveredby normal urothelium. During transurethral resection, the patientdeveloped hemodynamic crisis including sinus bradycardia.Histopathologic examination revealed a primary bladder composi...

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Veröffentlicht in:Canadian Urological Association journal 2013-05, Vol.3 (5), p.45
Hauptverfasser: Chen, C-H., Boag, Alexander H., Beiko, Darren T., Siemens, Robert, Froese, Alison, Isotalo, Phillip A.
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container_end_page
container_issue 5
container_start_page 45
container_title Canadian Urological Association journal
container_volume 3
creator Chen, C-H.
Boag, Alexander H.
Beiko, Darren T.
Siemens, Robert
Froese, Alison
Isotalo, Phillip A.
description A 64-year-old man presented with gross painless hematuria.Cystoscopy revealed a submucosal bladder neck mass coveredby normal urothelium. During transurethral resection, the patientdeveloped hemodynamic crisis including sinus bradycardia.Histopathologic examination revealed a primary bladder compositeparaganglioma-ganglioneuroma (CPG). The patient underwentpartial cystectomy and is symptom-free after one year. BladderCPGs are extremely rare neoplasms that may result in lifethreateningcatecholamine secretion, especially during tumourmanipulation. These tumours require complete surgical excisionand should be included in the differential diagnosis of any solitarybladder mass covered by normal urothelium, especially whenthere is a history of hypertension or micturition attacks.
doi_str_mv 10.5489/cuaj.1160
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title Composite paraganglioma-ganglioneuroma of the urinary bladder: a rare neoplasm causing hemodynamic crisis at tumour resection
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