Blood pressure and heart rate in aripiprazole once – monthly and paliperidone 1 and 3-month long-acting preparations
Objective: This study aims to evaluate the blood pressure and heart rates of the patients treated with aripiprazole once-monthly, paliperidone 1-month, and paliperidone 3-month long-acting injections. Patients and Methods: This study was a non-invasive observational study. Subjects using the same lo...
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| Veröffentlicht in: | Marmara Medical Journal 2023-05, Vol.36 (2), p.157-161 |
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| container_title | Marmara Medical Journal |
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| creator | SARIDOGAN, Gokce Elif GOREN, Mehmet Zafer |
| description | Objective: This study aims to evaluate the blood pressure and heart rates of the patients treated with aripiprazole once-monthly,
paliperidone 1-month, and paliperidone 3-month long-acting injections.
Patients and Methods: This study was a non-invasive observational study. Subjects using the same long-acting injection preparation
for at least four months without skipped injections were assigned to 3 groups according to their treatments. They were screened
starting from routine injection day and monthly for four months. Heart rate, systolic blood pressure, and diastolic blood pressure were
recorded for each subject.
Results: Systolic and diastolic blood pressure among the three treatment groups demonstrated no statistical significance. The heart rate
of the paliperidone 3-month group was significantly higher than the aripiprazole once-monthly group. However, the mean heart rate
was within the physiological limits. Thus, a clinical significance can hardly be attributed.
Conclusion: Aripiprazole once-monthly, paliperidone 1-month, and paliperidone 3-month long-acting injections are non-inferior
regarding heart rate, systolic and diastolic blood pressure during the maintenance treatment. |
| doi_str_mv | 10.5472/marumj.1302445 |
| format | Article |
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paliperidone 1-month, and paliperidone 3-month long-acting injections.
Patients and Methods: This study was a non-invasive observational study. Subjects using the same long-acting injection preparation
for at least four months without skipped injections were assigned to 3 groups according to their treatments. They were screened
starting from routine injection day and monthly for four months. Heart rate, systolic blood pressure, and diastolic blood pressure were
recorded for each subject.
Results: Systolic and diastolic blood pressure among the three treatment groups demonstrated no statistical significance. The heart rate
of the paliperidone 3-month group was significantly higher than the aripiprazole once-monthly group. However, the mean heart rate
was within the physiological limits. Thus, a clinical significance can hardly be attributed.
Conclusion: Aripiprazole once-monthly, paliperidone 1-month, and paliperidone 3-month long-acting injections are non-inferior
regarding heart rate, systolic and diastolic blood pressure during the maintenance treatment.</description><identifier>ISSN: 1019-1941</identifier><identifier>DOI: 10.5472/marumj.1302445</identifier><language>eng</language><ispartof>Marmara Medical Journal, 2023-05, Vol.36 (2), p.157-161</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c234t-f4921c066299092652ba20bddbd63492b48324e4dbada1dc8931b993b706c89f3</cites><orcidid>0000-0003-0049-2001 ; 0000-0002-8800-4043</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>SARIDOGAN, Gokce Elif</creatorcontrib><creatorcontrib>GOREN, Mehmet Zafer</creatorcontrib><title>Blood pressure and heart rate in aripiprazole once – monthly and paliperidone 1 and 3-month long-acting preparations</title><title>Marmara Medical Journal</title><description>Objective: This study aims to evaluate the blood pressure and heart rates of the patients treated with aripiprazole once-monthly,
paliperidone 1-month, and paliperidone 3-month long-acting injections.
Patients and Methods: This study was a non-invasive observational study. Subjects using the same long-acting injection preparation
for at least four months without skipped injections were assigned to 3 groups according to their treatments. They were screened
starting from routine injection day and monthly for four months. Heart rate, systolic blood pressure, and diastolic blood pressure were
recorded for each subject.
Results: Systolic and diastolic blood pressure among the three treatment groups demonstrated no statistical significance. The heart rate
of the paliperidone 3-month group was significantly higher than the aripiprazole once-monthly group. However, the mean heart rate
was within the physiological limits. Thus, a clinical significance can hardly be attributed.
Conclusion: Aripiprazole once-monthly, paliperidone 1-month, and paliperidone 3-month long-acting injections are non-inferior
regarding heart rate, systolic and diastolic blood pressure during the maintenance treatment.</description><issn>1019-1941</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNotkE1OwzAUhL0AiVLYsvYFUvwXN15CxZ9UiQ2so-fYaV0ltmWnSGXFHbghJyFNu3qaN6MZ6UPojpJFKZbsvoe073cLygkTorxAM0qoKqgS9Apd57wjpKyIkjP09diFYHBMNud9shi8wVsLacAJBoudx5BcdDHBd-gsDr6x-O_nF_fBD9vuMOUjdC7a5EzwFtPpxYspgLvgNwU0g_Ob40aEsdUFn2_QZQtdtrfnO0efz08fq9di_f7ytnpYFw3jYihaoRhtiJRMKaKYLJkGRrQx2kg-elpUnAkrjAYD1DSV4lQrxfWSyFG0fI4Wp94mhZyTbeuY3AjnUFNSH0nVJ1L1mRT_B8dxYg0</recordid><startdate>20230531</startdate><enddate>20230531</enddate><creator>SARIDOGAN, Gokce Elif</creator><creator>GOREN, Mehmet Zafer</creator><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0003-0049-2001</orcidid><orcidid>https://orcid.org/0000-0002-8800-4043</orcidid></search><sort><creationdate>20230531</creationdate><title>Blood pressure and heart rate in aripiprazole once – monthly and paliperidone 1 and 3-month long-acting preparations</title><author>SARIDOGAN, Gokce Elif ; GOREN, Mehmet Zafer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c234t-f4921c066299092652ba20bddbd63492b48324e4dbada1dc8931b993b706c89f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SARIDOGAN, Gokce Elif</creatorcontrib><creatorcontrib>GOREN, Mehmet Zafer</creatorcontrib><collection>CrossRef</collection><jtitle>Marmara Medical Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SARIDOGAN, Gokce Elif</au><au>GOREN, Mehmet Zafer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood pressure and heart rate in aripiprazole once – monthly and paliperidone 1 and 3-month long-acting preparations</atitle><jtitle>Marmara Medical Journal</jtitle><date>2023-05-31</date><risdate>2023</risdate><volume>36</volume><issue>2</issue><spage>157</spage><epage>161</epage><pages>157-161</pages><issn>1019-1941</issn><abstract>Objective: This study aims to evaluate the blood pressure and heart rates of the patients treated with aripiprazole once-monthly,
paliperidone 1-month, and paliperidone 3-month long-acting injections.
Patients and Methods: This study was a non-invasive observational study. Subjects using the same long-acting injection preparation
for at least four months without skipped injections were assigned to 3 groups according to their treatments. They were screened
starting from routine injection day and monthly for four months. Heart rate, systolic blood pressure, and diastolic blood pressure were
recorded for each subject.
Results: Systolic and diastolic blood pressure among the three treatment groups demonstrated no statistical significance. The heart rate
of the paliperidone 3-month group was significantly higher than the aripiprazole once-monthly group. However, the mean heart rate
was within the physiological limits. Thus, a clinical significance can hardly be attributed.
Conclusion: Aripiprazole once-monthly, paliperidone 1-month, and paliperidone 3-month long-acting injections are non-inferior
regarding heart rate, systolic and diastolic blood pressure during the maintenance treatment.</abstract><doi>10.5472/marumj.1302445</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-0049-2001</orcidid><orcidid>https://orcid.org/0000-0002-8800-4043</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Marmara Medical Journal, 2023-05, Vol.36 (2), p.157-161 |
| issn | 1019-1941 |
| language | eng |
| recordid | cdi_crossref_primary_10_5472_marumj_1302445 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| title | Blood pressure and heart rate in aripiprazole once – monthly and paliperidone 1 and 3-month long-acting preparations |
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