Safety of blood reinfusion after local infiltration analgesia with ropivacaine in total knee arthroplasty

The authors hypothesized that it is safe to combine local infiltration analgesia (LIA) in total knee arthroplasty (TKA) with a retransfusion drain since ropivacaine concentrations would not exceed the arterial toxicity threshold concentrations of 4.3 mg/L for total and 0.56 mg/L for unbound ropivaca...

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Veröffentlicht in:	International journal of clinical pharmacology and therapeutics 2014-02, Vol.52 (2), p.135-142
Hauptverfasser:	THOMASSEN, Bregje J. W, TOUW, Daan, VAN DER WOUDE, Pieter, VAN DER FLIER, Rudolf E, IN 'T VELD, Bastiaan A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amides - administration & dosage Amides - blood Analgesia - methods Anesthetics, Local - administration & dosage Arthroplasty, Replacement, Knee - methods Biological and medical sciences Blood Transfusion, Autologous - adverse effects Female Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments
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