Association of neutrophil/lymphocyte ratio and retinal vein occlusion
To evaluate the association between neutrophil/lymphocyte ratio (NLR) and the development of retinal vein occlusion (RVO). Forty patients were included in the study. Forty age- and sex-matched healthy volunteers were recruited as the control group. The RVO diagnosis was made clinically, based on the...
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| Veröffentlicht in: | European journal of ophthalmology 2015-07, Vol.25 (4), p.343-346 |
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| container_title | European journal of ophthalmology |
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| creator | Dursun, Ayhan Ozturk, Sultan Yucel, Hasan Ozec, Ayse Vural Dursun, Feyza Gulac Toker, Mustafa Ilker Erdogan, Haydar Arici, Mustafa Kemal Topalkara, Aysen |
| description | To evaluate the association between neutrophil/lymphocyte ratio (NLR) and the development of retinal vein occlusion (RVO).
Forty patients were included in the study. Forty age- and sex-matched healthy volunteers were recruited as the control group. The RVO diagnosis was made clinically, based on the findings of fundus examination. The NLR and file records of the patients and the control group were compared.
The mean age of patients was 64 ± 12 years. Neutrophil levels were higher in RVO patients compared to the control subjects (5.1 ± 1.9 vs 3.6 ± 1.0, p |
| doi_str_mv | 10.5301/ejo.5000570 |
| format | Article |
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Forty patients were included in the study. Forty age- and sex-matched healthy volunteers were recruited as the control group. The RVO diagnosis was made clinically, based on the findings of fundus examination. The NLR and file records of the patients and the control group were compared.
The mean age of patients was 64 ± 12 years. Neutrophil levels were higher in RVO patients compared to the control subjects (5.1 ± 1.9 vs 3.6 ± 1.0, p<0.001). Lymphocyte levels were lower in RVO patients compared with the control subjects (2.0 ± 0.7 vs 2.6 ± 0.9, p = 0.005). The NLR was significantly higher in RVO patients compared with the control subjects (3.0 ± 2.7 vs 1.5 ± 0.3, p<0.001). According to the receiver operator characteristics curve analysis, the optimal cutoff value of NLR to predict RVO was >1.89, with 72.5% sensitivity and 100% specificity.
The current study demonstrated that higher NLR was associated with the development of RVO. The NLR may be used as a predictive tool for identifying risk for RVO.</description><identifier>ISSN: 1120-6721</identifier><identifier>EISSN: 1724-6016</identifier><identifier>DOI: 10.5301/ejo.5000570</identifier><identifier>PMID: 25633622</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Female ; Fundus Oculi ; Humans ; Leukocyte Count ; Lymphocytes - pathology ; Male ; Middle Aged ; Neutrophils - pathology ; Retinal Vein Occlusion - blood ; Retinal Vein Occlusion - diagnosis ; ROC Curve</subject><ispartof>European journal of ophthalmology, 2015-07, Vol.25 (4), p.343-346</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c289t-7aaa81b36794ec4c07462560ca78e24615fcfe3dd14449e9197e8c27e6cb6e2c3</citedby><cites>FETCH-LOGICAL-c289t-7aaa81b36794ec4c07462560ca78e24615fcfe3dd14449e9197e8c27e6cb6e2c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25633622$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dursun, Ayhan</creatorcontrib><creatorcontrib>Ozturk, Sultan</creatorcontrib><creatorcontrib>Yucel, Hasan</creatorcontrib><creatorcontrib>Ozec, Ayse Vural</creatorcontrib><creatorcontrib>Dursun, Feyza Gulac</creatorcontrib><creatorcontrib>Toker, Mustafa Ilker</creatorcontrib><creatorcontrib>Erdogan, Haydar</creatorcontrib><creatorcontrib>Arici, Mustafa Kemal</creatorcontrib><creatorcontrib>Topalkara, Aysen</creatorcontrib><title>Association of neutrophil/lymphocyte ratio and retinal vein occlusion</title><title>European journal of ophthalmology</title><addtitle>Eur J Ophthalmol</addtitle><description>To evaluate the association between neutrophil/lymphocyte ratio (NLR) and the development of retinal vein occlusion (RVO).
Forty patients were included in the study. Forty age- and sex-matched healthy volunteers were recruited as the control group. The RVO diagnosis was made clinically, based on the findings of fundus examination. The NLR and file records of the patients and the control group were compared.
The mean age of patients was 64 ± 12 years. Neutrophil levels were higher in RVO patients compared to the control subjects (5.1 ± 1.9 vs 3.6 ± 1.0, p<0.001). Lymphocyte levels were lower in RVO patients compared with the control subjects (2.0 ± 0.7 vs 2.6 ± 0.9, p = 0.005). The NLR was significantly higher in RVO patients compared with the control subjects (3.0 ± 2.7 vs 1.5 ± 0.3, p<0.001). According to the receiver operator characteristics curve analysis, the optimal cutoff value of NLR to predict RVO was >1.89, with 72.5% sensitivity and 100% specificity.
The current study demonstrated that higher NLR was associated with the development of RVO. The NLR may be used as a predictive tool for identifying risk for RVO.</description><subject>Adult</subject><subject>Aged</subject><subject>Female</subject><subject>Fundus Oculi</subject><subject>Humans</subject><subject>Leukocyte Count</subject><subject>Lymphocytes - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neutrophils - pathology</subject><subject>Retinal Vein Occlusion - blood</subject><subject>Retinal Vein Occlusion - diagnosis</subject><subject>ROC Curve</subject><issn>1120-6721</issn><issn>1724-6016</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE1Lw0AQhhdRbK2evEvuknb2I7vJsZRWhYIXPYfNZEJTkmzYTYX8e1NaPc3APDPM-zD2zGGZSOArOrplAgCJgRs250aoWAPXt1PPBcTaCD5jDyEcAQRkStyzmUi0lFqIOduuQ3BY26F2XeSqqKPT4F1_qJtVM7b9weE4UOTP88h2ZeRpqDvbRD9UTzxicwrT5iO7q2wT6OlaF-x7t_3avMf7z7ePzXofo0izITbW2pQXUptMESoEo_T0CqA1KQmleVJhRbIsuVIqo4xnhlIUhjQWmgTKBXu93EXvQvBU5b2vW-vHnEN-lpFPMvKrjIl-udD9qWip_Gf_0stfHwlbJw</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Dursun, Ayhan</creator><creator>Ozturk, Sultan</creator><creator>Yucel, Hasan</creator><creator>Ozec, Ayse Vural</creator><creator>Dursun, Feyza Gulac</creator><creator>Toker, Mustafa Ilker</creator><creator>Erdogan, Haydar</creator><creator>Arici, Mustafa Kemal</creator><creator>Topalkara, Aysen</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20150701</creationdate><title>Association of neutrophil/lymphocyte ratio and retinal vein occlusion</title><author>Dursun, Ayhan ; Ozturk, Sultan ; Yucel, Hasan ; Ozec, Ayse Vural ; Dursun, Feyza Gulac ; Toker, Mustafa Ilker ; Erdogan, Haydar ; Arici, Mustafa Kemal ; Topalkara, Aysen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c289t-7aaa81b36794ec4c07462560ca78e24615fcfe3dd14449e9197e8c27e6cb6e2c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Female</topic><topic>Fundus Oculi</topic><topic>Humans</topic><topic>Leukocyte Count</topic><topic>Lymphocytes - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neutrophils - pathology</topic><topic>Retinal Vein Occlusion - blood</topic><topic>Retinal Vein Occlusion - diagnosis</topic><topic>ROC Curve</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dursun, Ayhan</creatorcontrib><creatorcontrib>Ozturk, Sultan</creatorcontrib><creatorcontrib>Yucel, Hasan</creatorcontrib><creatorcontrib>Ozec, Ayse Vural</creatorcontrib><creatorcontrib>Dursun, Feyza Gulac</creatorcontrib><creatorcontrib>Toker, Mustafa Ilker</creatorcontrib><creatorcontrib>Erdogan, Haydar</creatorcontrib><creatorcontrib>Arici, Mustafa Kemal</creatorcontrib><creatorcontrib>Topalkara, Aysen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>European journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dursun, Ayhan</au><au>Ozturk, Sultan</au><au>Yucel, Hasan</au><au>Ozec, Ayse Vural</au><au>Dursun, Feyza Gulac</au><au>Toker, Mustafa Ilker</au><au>Erdogan, Haydar</au><au>Arici, Mustafa Kemal</au><au>Topalkara, Aysen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of neutrophil/lymphocyte ratio and retinal vein occlusion</atitle><jtitle>European journal of ophthalmology</jtitle><addtitle>Eur J Ophthalmol</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>25</volume><issue>4</issue><spage>343</spage><epage>346</epage><pages>343-346</pages><issn>1120-6721</issn><eissn>1724-6016</eissn><abstract>To evaluate the association between neutrophil/lymphocyte ratio (NLR) and the development of retinal vein occlusion (RVO).
Forty patients were included in the study. Forty age- and sex-matched healthy volunteers were recruited as the control group. The RVO diagnosis was made clinically, based on the findings of fundus examination. The NLR and file records of the patients and the control group were compared.
The mean age of patients was 64 ± 12 years. Neutrophil levels were higher in RVO patients compared to the control subjects (5.1 ± 1.9 vs 3.6 ± 1.0, p<0.001). Lymphocyte levels were lower in RVO patients compared with the control subjects (2.0 ± 0.7 vs 2.6 ± 0.9, p = 0.005). The NLR was significantly higher in RVO patients compared with the control subjects (3.0 ± 2.7 vs 1.5 ± 0.3, p<0.001). According to the receiver operator characteristics curve analysis, the optimal cutoff value of NLR to predict RVO was >1.89, with 72.5% sensitivity and 100% specificity.
The current study demonstrated that higher NLR was associated with the development of RVO. The NLR may be used as a predictive tool for identifying risk for RVO.</abstract><cop>United States</cop><pmid>25633622</pmid><doi>10.5301/ejo.5000570</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1120-6721 |
| ispartof | European journal of ophthalmology, 2015-07, Vol.25 (4), p.343-346 |
| issn | 1120-6721 1724-6016 |
| language | eng |
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| source | MEDLINE; SAGE Complete |
| subjects | Adult Aged Female Fundus Oculi Humans Leukocyte Count Lymphocytes - pathology Male Middle Aged Neutrophils - pathology Retinal Vein Occlusion - blood Retinal Vein Occlusion - diagnosis ROC Curve |
| title | Association of neutrophil/lymphocyte ratio and retinal vein occlusion |
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