Current Antifungal Antibiotics

Recently, opportunistic fungal infections are becoming more important in the compromised patients. The review summarizes current attempts to find new and useful antifungal antibiotics mainly active against opportunistic fungal pathogens. Based on the chemical structures, antifungal antibiotics repor...

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Veröffentlicht in:	Journal of Synthetic Organic Chemistry, Japan Japan, 1993/04/01, Vol.51(4), pp.327-349
Hauptverfasser:	INOUYE, Shigeharu, SEZAKI, Masaji
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Alkylphenols Amino acids Antibiotics Antitungal activity Condensed polycyclic aromatics Cyclodepsipeptides Glycolipids Halogenopyrroles Lipopeptides Peptidonucleosides Polyene macrolides Screening methodology Terpenoids
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container_title	Journal of Synthetic Organic Chemistry, Japan
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creator	INOUYE, Shigeharu SEZAKI, Masaji
description	Recently, opportunistic fungal infections are becoming more important in the compromised patients. The review summarizes current attempts to find new and useful antifungal antibiotics mainly active against opportunistic fungal pathogens. Based on the chemical structures, antifungal antibiotics reported since 1987 are conveniently classified into 12 types : 1) polyene macrolide and related antibiotics, 2) lipopeptide antibiotics, 3) glycolipid antibiotics, 4) glycolipid/lipopeptide related antibiotics, 5) alkylphenol antibiotics, 6) terpenoid antibiotics, 7) cyclodepsipeptide antibiotics, 8) peptidonucleoside antibiotics, 9) amino acid antibiotics, 10) condensed polycyclic aromatic antibiotics, 11) halogenopyrrole antibiotics and 12) miscellaneous antibiotics. Finally, the principles and strategy for screening of antifungal antibiotics are discussed.
doi_str_mv	10.5059/yukigoseikyokaishi.51.327
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Finally, the principles and strategy for screening of antifungal antibiotics are discussed.</description><subject>Alkylphenols</subject><subject>Amino acids</subject><subject>Antibiotics</subject><subject>Antitungal activity</subject><subject>Condensed polycyclic aromatics</subject><subject>Cyclodepsipeptides</subject><subject>Glycolipids</subject><subject>Halogenopyrroles</subject><subject>Lipopeptides</subject><subject>Peptidonucleosides</subject><subject>Polyene macrolides</subject><subject>Screening methodology</subject><subject>Terpenoids</subject><issn>0037-9980</issn><issn>1883-6526</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><recordid>eNptj89OwzAMhyMEEtPYKyB4gBYnjtvkOFX8mTQJCcE5Sru0y1palHSHvT0dQ7uAD7YP_n7yx9g9h5SA9MNh3_pmiM63h6G1Pm59SjxFkV-wGVcKk4xEdslmAJgnWiu4ZosYdzAVKs1Rz9htsQ_B9ePdsh99ve8b2_2spR9GX8UbdlXbLrrF75yzj6fH9-IlWb8-r4rlOqmklGOilAQOGmQukDhhXTsqoayt0qIksFTJjUYulKANcrB8eoYE5lSWQtvM4ZzpU24VhhiDq81X8J82HAwHc3Q1f10NcTO5Tuzbid3F0TbuTNowGXTuH5JriUdantoUcj6utjYY1-M3T8Zqxg</recordid><startdate>1993</startdate><enddate>1993</enddate><creator>INOUYE, Shigeharu</creator><creator>SEZAKI, Masaji</creator><general>The Society of Synthetic Organic Chemistry, Japan</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1993</creationdate><title>Current Antifungal Antibiotics</title><author>INOUYE, Shigeharu ; SEZAKI, Masaji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-8840109047235153ffe5b0bfa892b50a5c4d9312825d310a199852375bb29a6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>1993</creationdate><topic>Alkylphenols</topic><topic>Amino acids</topic><topic>Antibiotics</topic><topic>Antitungal activity</topic><topic>Condensed polycyclic aromatics</topic><topic>Cyclodepsipeptides</topic><topic>Glycolipids</topic><topic>Halogenopyrroles</topic><topic>Lipopeptides</topic><topic>Peptidonucleosides</topic><topic>Polyene macrolides</topic><topic>Screening methodology</topic><topic>Terpenoids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>INOUYE, Shigeharu</creatorcontrib><creatorcontrib>SEZAKI, Masaji</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of Synthetic Organic Chemistry, Japan</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>INOUYE, Shigeharu</au><au>SEZAKI, Masaji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Current Antifungal Antibiotics</atitle><jtitle>Journal of Synthetic Organic Chemistry, Japan</jtitle><addtitle>J. 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language	eng ; jpn
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source	EZB-FREE-00999 freely available EZB journals
subjects	Alkylphenols Amino acids Antibiotics Antitungal activity Condensed polycyclic aromatics Cyclodepsipeptides Glycolipids Halogenopyrroles Lipopeptides Peptidonucleosides Polyene macrolides Screening methodology Terpenoids
title	Current Antifungal Antibiotics
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