In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets

In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets

The present work was to a comparative exploration of some physicochemical possessions viz., weight change, thickness, diameter, hardness, disintegration time, in-vitro drug discharge and analyse studies of various commercially available Pantoprazole sodium tablets (PST) of 40 mg. The hardness, loss...

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Veröffentlicht in:Kuwait journal of science 2021-01, Vol.48 (1), p.93-97
Hauptverfasser: Sravanthi, Pandyala, Haranath, Chinthaginjala, Dasari, Rahul Raghav, Gowthami, Madana, Varam, Naga Jyothi, Abd al-Ahad, Hindustan
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container_end_page 97
container_issue 1
container_start_page 93
container_title Kuwait journal of science
container_volume 48
creator Sravanthi, Pandyala
Haranath, Chinthaginjala
Dasari, Rahul Raghav
Gowthami, Madana
Varam, Naga Jyothi
Abd al-Ahad, Hindustan
description The present work was to a comparative exploration of some physicochemical possessions viz., weight change, thickness, diameter, hardness, disintegration time, in-vitro drug discharge and analyse studies of various commercially available Pantoprazole sodium tablets (PST) of 40 mg. The hardness, loss on friability, dissolution test, disintegration test and uniformity of drug content were evaluated. All the brands meet the requirements as per the pharmacopoeial standards. The dissolution profile study revealed that PST-1 had faster while PST-2 has slower. The dissolution informations were kinetically treated.
doi_str_mv 10.48129/kjs.v48i1.8598
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title In vitro proportional investigation of different Pantoprazole sodium brands of gastro-resistant tablets
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