Effects of a ethanol precipitated fraction of kabosu (Citrus sphaerocarpa Hort.) juice on cholesterol metabolism in rats

Using rat, we investigated the effects on cholesterol metabolism of an ethanol-precipitated fraction of Kabosu (Kabosu Juice Residue: KJR) obtained from 1 liter of Kabosu juice by adding 0.71 liter of ethanol. Male Sprague-Dawley strain rats, 4 weeks of age, were fed on a high cholesterol diet conta...

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Veröffentlicht in:Nihon Eiyō, Shokuryō Gakkai shi 1996, Vol.49(6), pp.337-341
Hauptverfasser: Mochizuki, S. (Oita Univ. (Japan). Faculty of Education), Yamamoto, A, Takahashi, M
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container_end_page 341
container_issue 6
container_start_page 337
container_title Nihon Eiyō, Shokuryō Gakkai shi
container_volume 49
creator Mochizuki, S. (Oita Univ. (Japan). Faculty of Education)
Yamamoto, A
Takahashi, M
description Using rat, we investigated the effects on cholesterol metabolism of an ethanol-precipitated fraction of Kabosu (Kabosu Juice Residue: KJR) obtained from 1 liter of Kabosu juice by adding 0.71 liter of ethanol. Male Sprague-Dawley strain rats, 4 weeks of age, were fed on a high cholesterol diet containing KJR. Serum and liver cholesterol levels decreased as the amount of administered KJR increased, and the excretion of fecal bile acids and neutral sterols was promoted. The secretion rate of cholesterol from the liver to the blood was lowered by the administration of KJR. From these results, promotion of the excretion of fecal bile acids and neutral sterols and depression of the secretion of cholesterol from the liver to the blood were considered to be the major mechanisms responsible for the cholesterol-lowering effect of KJR. The activity of the cholesterol-lowering effect of KJR was not weakened by administration of KJR which had been dry-heated or autoclaved
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From these results, promotion of the excretion of fecal bile acids and neutral sterols and depression of the secretion of cholesterol from the liver to the blood were considered to be the major mechanisms responsible for the cholesterol-lowering effect of KJR. 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subjects bile acids
CHOLESTEROL
cholesterol metabolism
CITRUS
COLESTEROL
ETANOL
ETHANOL
excretion
FRUIT JUICES
JUGO DE FRUTAS
JUS DE FRUITS
Kabosu
METABOLISM
METABOLISME
METABOLISMO
neutral sterols
secretion
title Effects of a ethanol precipitated fraction of kabosu (Citrus sphaerocarpa Hort.) juice on cholesterol metabolism in rats
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