MiR-452 negatively regulates osteoblast differentiation in periodontal ligament stem cells by targeting the polycomb-group protein, BMI1

Purpose: To determine whether miR-452 regulates osteoblast differentiation (OD) in human periodontal ligament stem cells (hPDLSCs) by targeting polycomb-group protein BMI1. Methods: hPDLSCs were stimulated to differentiate upon treatment with mineralization liquid. Quantitative real-time polymerase...

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Veröffentlicht in:Tropical journal of pharmaceutical research 2022-01, Vol.20 (4), p.797-802
Hauptverfasser: Mao, Tiantian, Li, Jun, Peng, Ruobing, Liu, Linhua, Peng, Youjian
Format: Artikel
Sprache:eng
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