Aspirin-aromatic amino acid conjugates as selective Cox-2 inhibitors: A docking study

Purpose: To examine eight compounds in which aspirin was conjugated with aromatic amino acids virtually using docking studies for their ability to inhibit cyclooxygenase 2 (Cox-2) enzyme. Methods: The compounds were drawn, energy minimised and then docked into the active site of Cox-2 along with cel...

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Veröffentlicht in:	Tropical journal of pharmaceutical research 2021-03, Vol.20 (3), p.579-583
Hauptverfasser:	Jasim, Mahmood H.M., Abed, Mohammed N., Qazzaz, Mohannad E., Alfahad, Mohanad, Alassaf, Fawaz A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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