Antidepressant effect of methanol root bark extract of Acacia seyal Del. (Fabaceae): Possible involvement of the inflammatory pathway

Purpose: To study the involvement of inflammatory pathways in the antidepressant activity of Acacia seyal in mice.Methods: The median lethal dose (LD50) of the extract Acacia seyal (AS) was determined using OECD guideline 425. The antidepressant activity of AS was assessed against BCG (0.2 mg/kg, ip...

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Veröffentlicht in:Tropical journal of pharmaceutical research 2020-07, Vol.19 (7), p.1459-1464
Hauptverfasser: Shehu, Aishatu, Anyip, Bishio, Magaji, Mohammed Garba
Format: Artikel
Sprache:eng
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