Florofangchinoline inhibits proliferation of osteosarcoma cells via targeting of histone H3 lysine 27 trimethylation and AMPK activation

Purpose: To investigate the effect of florofangchinoline on osteosarcoma cell growth in vitro, and the underlying mechanism of action.Methods: Changes in the viability of KHOS and Saos-2 cells were measured using water soluble tetrazolium salt (WST) assay, while apoptosis was determined using Annexi...

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Veröffentlicht in:Tropical journal of pharmaceutical research 2020-07, Vol.19 (7), p.1403-1409
Hauptverfasser: Zhao, Liyan, Liu, Xiongtao, Zhu, Weina, Yang, Pei, Qin, Jie, Gu, Ru, Zhao, Zhili
Format: Artikel
Sprache:eng
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