In vitro Evaluation of PEGylated-Mucin Matrix as Carrier for Oral Delivery of Metformin Hydrochloride

Purpose:To formulate metformin hydrochloride-loaded PEGylated-mucin microparticles and evaluate their in vitro properties. Method: Three different formulations of metformin hydrochloride (MTH) (PEG-M1, PEG-M2 and PEG- M3) were prepared using PEGylation method. PEG-8000 and snail mucin, in a ratio of...

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Veröffentlicht in:	Tropical journal of pharmaceutical research 2014-09, Vol.13 (7), p.1039
Hauptverfasser:	Momoh, M.A, Adedokun, M.O, Adikwu, M.U, Ibezim, C.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug delivery Encapsulation Extended release Mucin PEGylation Polydispersity index Polyethylene glycol Zeta potential
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