Formulation and Evaluation of Tramadol HCl Matrix Tablets Using Carbopol 974P and 934 as Rate-Controlling Agents

Purpose: To formulate and prepare controlled release (CR) matrix tablets of tramadol HCl using Carbopol 974P and 934 polymers as rate-controlling agents. Methods: The tablets were prepared by direct compression method using various drug to polymer (D:P) ratios. Co-excipients, including carboxymethyl...

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Veröffentlicht in:	Tropical journal of pharmaceutical research 2013-04, Vol.12 (2)
Hauptverfasser:	Rehman, Asim.ur, Khan, Gul M, Shah, Kifayat U, Shah, Shefaat U, Khan, Kamran A
Format:	Artikel
Sprache:	eng
Schlagworte:	Tramadol, Carbopol, Carboxymethylcellulose (CMC), Hydroxypropyl methylcellulose, Controlled release
Online-Zugang:	Volltext
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