Characterization and long-term persistence of immune response following two doses of an AS03A-adjuvanted H1N1 influenza vaccine in healthy Japanese adults

Background Long-term persistence of immune response and safety of two doses of an A/California/07/2009 H1N1 pandemic influenza vaccine adjuvanted with AS03 (an α-tocopherol oil-in-water emulsion-based Adjuvant System) administered 21 d apart was evaluated in Japanese adults [NCT00989612]. Methods On...

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Veröffentlicht in:	Human vaccines & immunotherapeutics 2012-02, Vol.8 (2), p.260-266
Hauptverfasser:	Ikematsu, Hideyuki, Nagai, Hideaki, Kawashima, Masahiro, Kawakami, Yasunobu, Tenjinbaru, Kazuyoshi, Li, Ping, Walravens, Karl, Gillard, Paul, Roman, François
Format:	Artikel
Sprache:	eng
Schlagworte:	adjuvant Adjuvants, Immunologic Adult Antibodies, Neutralizing - blood Antibodies, Neutralizing - immunology Antibodies, Viral - blood Antibodies, Viral - immunology AS03 Binding Biology Bioscience Calcium Cancer Cell Cycle Female H1N1 Hemagglutination Inhibition Tests Hemagglutinin Glycoproteins, Influenza Virus - immunology Humans Influenza A Virus, H1N1 Subtype - immunology Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Japan Landes long-term Male Middle Aged Organogenesis pandemic persistence Proteins Research Paper Time Factors Vaccination Young Adult
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