Protective effects of alanyl-glutamine supplementation against nelfinavir-induced epithelial impairment in IEC-6 cells and in mouse intestinal mucosa

Purpose: Human Immunodefiency Virus (HIV) protease inhibitors (PI) remain a crucial component of highly active therapy (HAART) and recently have been demonstrated to have potent antitumor effect on a wide variety of tumor cell lines. However, discontinuation of therapy is an important issue, which m...

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Veröffentlicht in:Cancer biology & therapy 2012-12, Vol.13 (14), p.1482-1490
Hauptverfasser: Braga-Neto, Manuel B., Oliveira, Bruna M.C., Rodrigues, Raphael S., Noronha, Francisco J., Leitao, Renata F., Brito, Gerly A.C., Lima, Aldo A., Guerrant, Richard L., Warren, Cirle A.
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Sprache:eng
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