Solid-state characterization of ibuprofen-isonicotinamide cocrystals prepared by electrospraying and solvent evaporation

Electrospraying (ELS) was used to prepare micronized ibuprofen-isonicotinamide cocrystal (IBU-INA-ELS) and its properties were compared with the solvent evaporated cocrystal (IBU-INA-SE). Solid-state characterization of crystalline phase, production yield, particle size, powder flow, wettability, so...

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Veröffentlicht in:	Therapeutic delivery 2023-02, Vol.14 (2), p.121-138
Hauptverfasser:	Ghafari, Reza, Jahangiri, Azin, Shayanfar, Ali, Emami, Shahram
Format:	Artikel
Sprache:	eng
Schlagworte:	cocrystal dissolution electrospraying Ibuprofen isonicotinamide phase transformation Powders - chemistry Solubility Solvents X-Ray Diffraction
Online-Zugang:	Volltext
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