Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring
Accurate detection and monitoring of therapeutic drug levels are vital for effective patient care and treatment management. Aptamers, composed of single-stranded DNA or RNA molecules, are integral components of biosensors designed for both qualitative and quantitative detection of biological samples...
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| Veröffentlicht in: | Bioanalysis 2023-12, Vol.15 (23), p.1439-1460 |
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| container_title | Bioanalysis |
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| creator | Lafi, Zainab Gharaibeh, Lobna Nsairat, Hamdi Asha, Nisreen Alshaer, Walhan |
| description | Accurate detection and monitoring of therapeutic drug levels are vital for effective patient care and treatment management. Aptamers, composed of single-stranded DNA or RNA molecules, are integral components of biosensors designed for both qualitative and quantitative detection of biological samples. Aptasensors play crucial roles in target identification, validation, detection of drug–target interactions and screening potential of drug candidates. This review focuses on the pivotal role of aptasensors in early disease detection, particularly in identifying biomarkers associated with various diseases such as cancer, infectious diseases and cardiovascular disorders. Aptasensors have demonstrated exceptional potential in enhancing disease diagnostics and monitoring therapeutic drug levels. Aptamer-based biosensors represent a transformative technology in the field of healthcare, enabling precise diagnostics, drug monitoring and disease detection. |
| doi_str_mv | 10.4155/bio-2023-0141 |
| format | Article |
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Aptamer-based biosensors represent a transformative technology in the field of healthcare, enabling precise diagnostics, drug monitoring and disease detection.</description><subject>aptasensors</subject><subject>biomaterial analysis</subject><subject>biosensors</subject><subject>diagnosis</subject><subject>personalized medicine</subject><subject>therapeutic monitoring</subject><issn>1757-6180</issn><issn>1757-6199</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1UD1PwzAUtBBIVKUju_9AwHadOGarKr6kSiwwMViO_VwZJXZkJ0P_PQ5FbLzlfeju9O4QuqXkjtO6vu98rBhh24pQTi_QiopaVA2V8vJvbsk12uT8RUptWSu5XKHP3TjpDCHHlB8wDGMfTz4c8RB7MHOvEx5T7CBjF5cRjM-AB7De6B5br48h5smbjHWw2KZ5YQY_xVREbtCV032GzW9fo4-nx_f9S3V4e37d7w6VYaKZKuB1Z0UNvDxLJXEtF0S0zBQzjoCVpitHySmIbSeYM21riK61aGjDGltQa1SddU2KOSdwakx-0OmkKFFLOKqEo5Zw1BJOwcsz3s3TnCAbD8GAOm8_3nyAf7jflvVscA</recordid><startdate>20231201</startdate><enddate>20231201</enddate><creator>Lafi, Zainab</creator><creator>Gharaibeh, Lobna</creator><creator>Nsairat, Hamdi</creator><creator>Asha, Nisreen</creator><creator>Alshaer, Walhan</creator><general>Newlands Press Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0003-2847-2416</orcidid><orcidid>https://orcid.org/0000-0001-5916-5879</orcidid><orcidid>https://orcid.org/0000-0003-2946-7328</orcidid></search><sort><creationdate>20231201</creationdate><title>Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring</title><author>Lafi, Zainab ; Gharaibeh, Lobna ; Nsairat, Hamdi ; Asha, Nisreen ; Alshaer, Walhan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c276t-e45bd75e4199190f8470782c023f0ed9cb90f941e73b72fc88c0a5a761626d023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>aptasensors</topic><topic>biomaterial analysis</topic><topic>biosensors</topic><topic>diagnosis</topic><topic>personalized medicine</topic><topic>therapeutic monitoring</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lafi, Zainab</creatorcontrib><creatorcontrib>Gharaibeh, Lobna</creatorcontrib><creatorcontrib>Nsairat, Hamdi</creatorcontrib><creatorcontrib>Asha, Nisreen</creatorcontrib><creatorcontrib>Alshaer, Walhan</creatorcontrib><collection>CrossRef</collection><jtitle>Bioanalysis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lafi, Zainab</au><au>Gharaibeh, Lobna</au><au>Nsairat, Hamdi</au><au>Asha, Nisreen</au><au>Alshaer, Walhan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring</atitle><jtitle>Bioanalysis</jtitle><date>2023-12-01</date><risdate>2023</risdate><volume>15</volume><issue>23</issue><spage>1439</spage><epage>1460</epage><pages>1439-1460</pages><issn>1757-6180</issn><eissn>1757-6199</eissn><abstract>Accurate detection and monitoring of therapeutic drug levels are vital for effective patient care and treatment management. 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| ispartof | Bioanalysis, 2023-12, Vol.15 (23), p.1439-1460 |
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| language | eng |
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| source | PubMed Central |
| subjects | aptasensors biomaterial analysis biosensors diagnosis personalized medicine therapeutic monitoring |
| title | Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring |
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