Determination of favipiravir in human plasma using homogeneous liquid–liquid microextraction followed by HPLC/UV

Favipiravir is an antiviral drug that was recently approved for the management of COVID-19 infection. This work aimed to develop a new method, using sugaring-out induced homogeneous liquid–liquid microextraction followed by HPLC/UV for the determination of favipiravir in human plasma. The optimum ex...

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Veröffentlicht in:	Bioanalysis 2022-02, Vol.14 (4), p.205-216
Hauptverfasser:	Abdallah, Inas A, Hammad, Sherin F, Bedair, Alaa, Elshafeey, Ahmed H, Mansour, Fotouh R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amides - administration & dosage Amides - blood Antiviral Agents - administration & dosage Antiviral Agents - blood bioequivalence Chromatography, High Pressure Liquid - methods COVID-19 COVID-19 - drug therapy Drug Monitoring - methods favipiravir FDA Humans Limit of Detection Liquid Phase Microextraction - methods microextraction Pyrazines - administration & dosage Pyrazines - blood SARS-CoV-2 - drug effects sugaring-out
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