Analytical and bioanalytical HPLC method for simultaneous estimation of 5-fluorouracil and sonidegib

To develop a new sensitive RP-HPLC method for simultaneous estimation of 5-fluorouracil (5-FU) and sonidegib (SDG). Analytical and bioanalytical methods for simultaneous quantification of 5-FU and SDG in bulk, nanoformulations and in rat plasma were developed and validated using a gradient elution t...

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Veröffentlicht in:	Bioanalysis 2022-01, Vol.14 (1), p.29-45
Hauptverfasser:	Padya, Bharath S, Hegde, Aswathi R, Mutalik, Sadhana P, Biswas, Swati, Mutalik, Srinivas
Format:	Artikel
Sprache:	eng
Schlagworte:	5-fluorouracil Animals bioanalytical Biphenyl Compounds - pharmacokinetics Chromatography, High Pressure Liquid - methods Fluorouracil - pharmacokinetics Male Neoplasms - drug therapy Pyridines - pharmacokinetics Rats Rats, Wistar RP-HPLC simultaneous estimation sonidegib
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