17β-Estradiol Promotes TLR4-Triggered Proinflammatory Mediator Production through Direct Estrogen Receptor α Signaling in Macrophages In Vivo

17β-estradiol (E2) has been shown to promote the expression of inflammatory mediators by LPS-activated tissue resident macrophages through estrogen receptor α (ERα) signaling. However, it remained to be determined whether E2 similarly influences macrophages effector functions under inflammatory cond...

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Veröffentlicht in:The Journal of immunology (1950) 2010-07, Vol.185 (2), p.1169-1176
Hauptverfasser: Calippe, Bertrand, Douin-Echinard, Victorine, Delpy, Laurent, Laffargue, Muriel, Lélu, Karine, Krust, Andrée, Pipy, Bernard, Bayard, Francis, Arnal, Jean-François, Guéry, Jean-Charles, Gourdy, Pierre
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Sprache:eng
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