Cutting Edge: H-2Ld Class I Molecule Protects an HIV N-Extended Epitope from In Vitro Trimming by Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing

In the classical MHC class I Ag presentation pathway, antigenic peptides derived from viral proteins by multiple proteolytic cleavages are transported to the endoplasmic reticulum lumen and are then exposed to ami-nopeptidase activity. In the current study, a long MHC class I natural ligand recogniz...

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Veröffentlicht in:	The Journal of immunology (1950) 2010-04, Vol.184 (7), p.3351-3355
Hauptverfasser:	Infantes, Susana, Samino, Yolanda, Lorente, Elena, Jimenez, Mercedes, Garcia, Ruth, Del Val, Margarita, Lopez, Daniel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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