β1 Integrin-Dependent Engulfment of Yersinia enterocolitica by Macrophages Is Coupled to the Activation of Autophagy and Suppressed by Type III Protein Secretion

Autophagy is a central lysosomal degradation process that is essential for the maintenance of cellular homeostasis. Autophagy has furthermore emerged as integral part of the host immune response. Autophagic processes promote the separation and degradation of intracellular microorganisms which contri...

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Veröffentlicht in:The Journal of immunology (1950) 2009-11, Vol.183 (9), p.5847-5860
Hauptverfasser: Deuretzbacher, Anne, Czymmeck, Nicole, Reimer, Rudolph, Trülzsch, Konrad, Gaus, Kristin, Hohenberg, Heinrich, Heesemann, Jürgen, Aepfelbacher, Martin, Ruckdeschel, Klaus
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Sprache:eng
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