Class I HLA Folding and Antigen Presentation in β2-Microglobulin-Defective Daudi Cells

To present virus and tumor Ags, HLA class I molecules undergo a complex multistep assembly involving discrete but transient folding intermediates. The most extensive folding abnormalities occur in cells lacking the class I L chain subunit, called β2-microglobulin (β2m). Herein, this issue was invest...

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Veröffentlicht in:	The Journal of immunology (1950) 2009-03, Vol.182 (6), p.3609-3617
Hauptverfasser:	Martayan, Aline, Sibilio, Leonardo, Tremante, Elisa, Monaco, Elisa Lo, Mulder, Arend, Fruci, Doriana, Cova, Agata, Rivoltini, Licia, Giacomini, Patrizio
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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