Ganodermanontriol Suppresses the Progression of Lung Adenocarcinoma by Activating CES2 to Enhance the Metabolism of Mycophenolate Mofetil

New anti-lung cancer therapies are urgently required to improve clinical outcomes. Since ganodermanontriol (GDNT) has been identified as a potential antineoplastic agent, its role in lung adenocarcinoma (LUAD) is investigated in this study. Concretely, lung cancer cells were treated with GDNT and/or...

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Veröffentlicht in:	Journal of microbiology and biotechnology 2024-02, Vol.34 (2), p.249-261
Hauptverfasser:	Xie, Qingfeng, Cao, Zhuo, You, Weiling, Cai, Xiaoping, Shen, Mei, Yin, Zhangyong, Jiang, Yiwei, Wang, Xin, Ye, Siyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma of Lung - drug therapy Animals Antineoplastic Agents - pharmacology Carboxylesterase Humans Lanosterol - analogs & derivatives Lung Neoplasms - drug therapy Mice Mycophenolic Acid - pharmacology
Online-Zugang:	Volltext
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