B-cell Chronic Lymphocytic Leukemia is Complicated by Autoimmune Hemolytic Anemia and Anti-phospholipid Syndrome

We describe a rare case of a 68-year-old man with B-cell chronic lymphocytic leukemia (B-CLL) who developed autoimmune hemolytic anemia (AIHA) and anti-phospholipid syndrome (APS). On admission, he was diagnosed as having B-CLL and AIHA on the basis of CD5-positive B-lymphocytes infiltrated into his...

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Veröffentlicht in:	Journal of Clinical and Experimental Hematopathology 2002, Vol.42(2), pp.75-79
Hauptverfasser:	Ikeda, Kazuhiko, Shichishima, Tsutomu, Yui, Tokuo, Otake, Atsushi, Sakai, Kazuyoshi, Noji, Hideyoshi, Nakamura, Naoya, Abe, Masafumi, Maruyama, Yukio
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-phospholipid syndrome autoimmune hemolytic anemia B-cell chronic lymphocytic leukemia deep-vein thrombosis lupus anticoagulant
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container_title	Journal of Clinical and Experimental Hematopathology
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creator	Ikeda, Kazuhiko Shichishima, Tsutomu Yui, Tokuo Otake, Atsushi Sakai, Kazuyoshi Noji, Hideyoshi Nakamura, Naoya Abe, Masafumi Maruyama, Yukio
description	We describe a rare case of a 68-year-old man with B-cell chronic lymphocytic leukemia (B-CLL) who developed autoimmune hemolytic anemia (AIHA) and anti-phospholipid syndrome (APS). On admission, he was diagnosed as having B-CLL and AIHA on the basis of CD5-positive B-lymphocytes infiltrated into his bone marrow and a positive Coombs test, respectively. Although the symptoms of B-CLL and AIHA were improved by chemotherapy, he developed deep-vein thrombosis, which was probably caused by a lupus anticoagulant. It was interesting that the thrombosis due to APS occurred following a decrease of hemolysis from AIHA after intensive chemotherapy.
doi_str_mv	10.3960/jslrt.42.75
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subjects	anti-phospholipid syndrome autoimmune hemolytic anemia B-cell chronic lymphocytic leukemia deep-vein thrombosis lupus anticoagulant
title	B-cell Chronic Lymphocytic Leukemia is Complicated by Autoimmune Hemolytic Anemia and Anti-phospholipid Syndrome
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