Luteolin Alleviates Alcoholic Liver Disease Induced by Chronic and Binge Ethanol Feeding in Mice

Ethanol consumption can lead to hepatic steatosis that contributes to late-stage liver diseases such as cirrhosis and hepatocellular carcinoma. In this study, we investigated the potential protective effect of a flavonoid, luteolin, on ethanol-induced fatty liver development and liver injury. Six-wk...

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Veröffentlicht in:	The Journal of nutrition 2014-07, Vol.144 (7), p.1009-1015
Hauptverfasser:	Liu, Gaigai, Zhang, Yuxue, Liu, Chunchun, Xu, Daqian, Zhang, Rui, Cheng, Yuan, Pan, Yi, Huang, Cheng, Chen, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism - physiopathology Animals Antioxidants - metabolism Antioxidants - therapeutic use Binge Drinking - physiopathology Biological and medical sciences Cell Line Dietary Supplements Disease Models, Animal Ethanol - antagonists & inhibitors Ethanol - toxicity Fatty Liver, Alcoholic - etiology Fatty Liver, Alcoholic - metabolism Fatty Liver, Alcoholic - pathology Fatty Liver, Alcoholic - prevention & control Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Regulation Hepatitis, Alcoholic - etiology Hepatitis, Alcoholic - metabolism Hepatitis, Alcoholic - pathology Hepatitis, Alcoholic - prevention & control Hepatocytes - drug effects Hepatocytes - metabolism Hepatocytes - pathology Humans Lipogenesis Liver - metabolism Liver - pathology Liver - physiopathology Liver Diseases, Alcoholic - etiology Liver Diseases, Alcoholic - metabolism Liver Diseases, Alcoholic - pathology Liver Diseases, Alcoholic - prevention & control Liver. Biliary tract. Portal circulation. Exocrine pancreas Luteolin - metabolism Luteolin - therapeutic use Male Medical sciences Mice Mice, Inbred C57BL Other diseases. Semiology Random Allocation Specific Pathogen-Free Organisms Vertebrates: anatomy and physiology, studies on body, several organs or systems
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