Mode of Action: Moving toward a More Relevant and Efficient Assessment Paradigm

To advance the utility and predictability of safety evaluation, an integrated approach that relies on all existing knowledge to understand how agents perturb normal biological function or structure is needed to progress more focused evaluation strategies. The mode of action (MOA)-human relevance fra...

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Veröffentlicht in:	The Journal of nutrition 2012-12, Vol.142 (12), p.2192S-2198S
Hauptverfasser:	DELLARCO, Vicki, FENNER-CRISP, Penelope A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chemical Safety Dose-Response Relationship, Drug Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Humans Risk Assessment Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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