Resveratrol Arrests and Regresses the Development of Pressure Overload- but Not Volume Overload-Induced Cardiac Hypertrophy in Rats

Cardiac hypertrophy is a compensatory enlargement of the heart due to either volume overload (VO) and/or pressure overload (PO) that develops into heart failure if left untreated. The polyphenol resveratrol has been reported to regress PO-induced cardiac hypertrophy in rats. Our aim in this study wa...

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Veröffentlicht in:	The Journal of nutrition 2010-05, Vol.140 (5), p.962-968
Hauptverfasser:	Wojciechowski, Peter, Juric, Danijel, Louis, Xavier Lieben, Thandapilly, Sijo Joseph, Yu, Liping, Taylor, Carla, Netticadan, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals Antioxidants - pharmacology Antioxidants - therapeutic use cardiac hypertrophy Cardiomegaly - drug therapy Cardiomegaly - etiology Cardiomegaly - physiopathology diet therapy Disease Models, Animal functional foods heart Heart - drug effects Lipid Peroxidation - drug effects Male Myocardium - metabolism Myocardium - pathology oxidative stress Oxidative Stress - drug effects Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use protective effect Rats Rats, Sprague-Dawley Resveratrol Stilbenes - pharmacology Stilbenes - therapeutic use Ventricular Pressure
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