Gene expression profile of residual breast cancer after doxorubicin and cyclophosphamide neoadjuvant chemotherapy

In breast cancer patients, primary chemotherapy is associated with the same survival benefits as adjuvant chemotherapy. Residual tumors represent a clinical challenge, as they may be resistant to additional cycles of the same drugs. Our aim was to identify differential transcripts expressed in resid...

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Veröffentlicht in:	Oncology reports 2009-10, Vol.22 (4), p.805-813
Hauptverfasser:	AZEVEDO KOIKE FOLGUEIRA, Maria Aparecida, BRENTANI, Helena, MOURAO, Mario, FIGARO CALDEIRA, José Roberto, MITZI BRENTANI, Maria, CARRARO, Dirce Maria, DE CAMARGO BARROS, Mateus, HIRATA KATAYAMA, Maria Lucia, SANTANA DE ABREU, Ana Paula, MANTOVANI BARBOSA, Edson, TOSELLO DE OLIVEIRA, Celia, PATRAO, Diogo F. C, MOTA, Louise D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomarkers, Tumor - genetics Breast Neoplasms - drug therapy Breast Neoplasms - genetics Connective Tissue Growth Factor - biosynthesis Connective Tissue Growth Factor - drug effects Connective Tissue Growth Factor - genetics Cyclophosphamide - administration & dosage Doxorubicin - administration & dosage Drug Resistance, Neoplasm - genetics Dual Specificity Phosphatase 1 - biosynthesis Dual Specificity Phosphatase 1 - drug effects Dual Specificity Phosphatase 1 - genetics Female Gene Expression - drug effects Gene Expression Profiling Gynecology. Andrology. Obstetrics Humans Mammary gland diseases MAP Kinase Kinase 4 - metabolism Medical sciences Middle Aged Neoadjuvant Therapy Neoplasm, Residual Oligonucleotide Array Sequence Analysis Reverse Transcriptase Polymerase Chain Reaction Signal Transduction - genetics Tumors
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