Identification of a methylation hotspot in the death receptor Fas/CD95 in bladder cancer

We characterized Fas immunoreactivity, functionality and its role in the response to mitomycin-C (MMC) chemotherapy in vitro in cell lines and in vivo in bladder washings from 23 transitional cell carcinoma of the bladder (TCCB) patients, harvested prior to and during MMC intravesical treatment. Hav...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of oncology 2012-03, Vol.40 (3), p.645-654
Hauptverfasser:	WATSON, C. J, O'KANE, H, MAXWELL, P, SHARAF, O, PETAK, I, HYLAND, P. L, O'ROUKE, D, MCKNIGHT, J, CANNING, P, WILLIAMSON, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apoptosis - genetics Apoptosis - immunology Biological and medical sciences Caco-2 Cells Carcinoma, Transitional Cell - genetics Carcinoma, Transitional Cell - immunology Cell Line, Tumor CpG Islands DNA Methylation Drug Resistance, Neoplasm Exons Fas Ligand Protein - genetics Fas Ligand Protein - immunology fas Receptor - genetics fas Receptor - immunology Female Follow-Up Studies Gene Silencing Genes, p53 Humans Introns Male Medical sciences Mitomycin - therapeutic use Mutation Nephrology. Urinary tract diseases Promoter Regions, Genetic Receptors, Death Domain - genetics Receptors, Death Domain - immunology Transfection - methods Tumors Tumors of the urinary system Up-Regulation Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - immunology Urinary tract. Prostate gland
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!