Endosialin: A novel malignant cell therapeutic target for neuroblastoma

Endosialin emerged recently as a potential therapeutic target for sarcoma. Since some sarcoma subtypes, such as Ewing's sarcoma, show characteristics of neuroendocrine differentiation, we wondered whether cancers with neuro-endocrine properties and/or neuroectodermal origin, such as neuroblasto...

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Veröffentlicht in:	International journal of oncology 2011-10, Vol.39 (4), p.841-851
Hauptverfasser:	ROULEAU, Cecile, SMALE, Robert, DUNHAM, Sarah, KRUMBHOLZ, Roy, CURIEL, Maritza, WALLAR, Gina, MASCARELLO, James, CAMPOS-RIVERA, Juanita, HORTEN, Bruce, SCHMID, Steven, MILLER, Glenn, TEICHER, Beverly A, SANCHO, Jose, FU, Yao-Shi, KURTZBERG, Leslie, WEBER, William, KRUGER, Ariel, JONES, Craig, ROTH, Stephanie, BORMANN, Christy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - biosynthesis Antigens, CD - genetics Antigens, CD - metabolism Antigens, Neoplasm - biosynthesis Antigens, Neoplasm - genetics Antigens, Neoplasm - metabolism Biological and medical sciences Cell Line, Tumor Humans Immunohistochemistry - methods Lung Neoplasms Medical sciences Melanoma - genetics Melanoma - metabolism Mice Molecular Targeted Therapy Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - pathology Neuroblastoma - genetics Neuroblastoma - metabolism Neuroblastoma - pathology Neurology Sarcoma - genetics Sarcoma - metabolism Side-Population Cells - metabolism Small Cell Lung Carcinoma - metabolism Small Cell Lung Carcinoma - pathology Transplantation, Heterologous Tumors Tumors of the nervous system. Phacomatoses
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