Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy

microRNAs (miRNAs) are small non-coding RNAs with important post-transcriptional regulatory functions. miRNA-21 (miR-21) is upregulated and miR-143 and miR-145 are downregulated in colorectal carcinoma. The aim of our study was to determine if these miRNAs change their expression levels in response...

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Veröffentlicht in:	International journal of oncology 2011-08, Vol.39 (2), p.409-415
Hauptverfasser:	DREBBER, Uta, LAY, Max, WEDEMEYER, Inga, VALLBÖHMER, Daniel, BOLLSCHWEILER, Elfriede, BRABENDER, Jan, MÖNIG, Stefan P, HÖLSCHER, Arnulf H, DIENES, Hans P, ODENTHAL, Margarete
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - therapeutic use Biological and medical sciences Biomarkers, Tumor - metabolism Female Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Profiling Gene Expression Regulation, Neoplastic - genetics Humans Male Medical sciences MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Neoadjuvant Therapy Neoplasm Staging Prognosis Radiotherapy Rectal Neoplasms - diagnosis Rectal Neoplasms - genetics Rectal Neoplasms - mortality Rectal Neoplasms - pathology Rectal Neoplasms - therapy Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Survival Analysis Treatment Outcome Tumors
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