Anti‑EGFR monoclonal antibody 134‑mG2a exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma

The epidermal growth factor receptor (EGFR), a transmembrane receptor and member of the human epidermal growth factor receptor (HER) family of receptor tyrosine kinases, is a critical mediator of cell growth and differentiation. EGFR forms homo- or heterodimers with other HER family members to activ...

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Veröffentlicht in:	International journal of molecular medicine 2020-10, Vol.46 (4), p.1443-1452
Hauptverfasser:	Hosono, Hideki, Takei, Junko, Ohishi, Tomokazu, Sano, Masato, Asano, Teizo, Sayama, Yusuke, Nakamura, Takuro, Yanaka, Miyuki, Kawada, Manabu, Harada, Hiroyuki, Kaneko, Mika, Kato, Yukinari
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Antibodies Cancer therapies Cytotoxicity Epidermal growth factor Experiments Flow cytometry Kinases Laboratories Monoclonal antibodies Oral cancer Radiation therapy Squamous cell carcinoma
Online-Zugang:	Volltext
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