Mitigation of 2,4-dinitrofluorobenzene-induced atopic dermatitis-related symptoms by Terminalia chebula Retzius

To evaluate whether an aqueous seed extract of Terminalia chebula Retzius inhibited development of atopy in vivo, we used a 2,4-dinitrofluorobenzene (DNFB)-induced animal model of atopic symptoms to investigate the effects of the extract. We measured CD4+ cell numbers by hematoxylin and eosin (H&...

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Veröffentlicht in:	International journal of molecular medicine 2011-12, Vol.28 (6), p.1013-1018
Hauptverfasser:	Nam, Dong-Yoon, Lee, Jin-Man, Heo, Jin-Chul, Lee, Sang-Han
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Dermatitis, Atopic - chemically induced Dermatitis, Atopic - drug therapy Dermatitis, Atopic - immunology Dermatitis, Atopic - metabolism Dermatitis, Atopic - pathology Dinitrofluorobenzene - adverse effects Eosine Yellowish-(YS) Eosinophils - drug effects Eosinophils - immunology Eosinophils - metabolism Hematoxylin Interleukins - analysis Interleukins - biosynthesis Male Matrix Metalloproteinase 9 - analysis Matrix Metalloproteinase 9 - biosynthesis Mice Mice, Inbred C57BL Phytotherapy - methods Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Seeds - chemistry Skin - drug effects Skin - immunology Skin - pathology T-Box Domain Proteins - analysis T-Box Domain Proteins - biosynthesis Terminalia - chemistry
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