Proteomic profiling of non-obese type 2 diabetic skeletal muscle

Abnormal glucose handling has emerged as a major clinical problem in millions of diabetic patients worldwide. Insulin resistance affects especially one of the main target organs of this hormone, the skeletal musculature, making impaired glucose metabolism in contractile fibres a major feature of typ...

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Veröffentlicht in:	International journal of molecular medicine 2010-03, Vol.25 (3), p.445-458
Hauptverfasser:	Mullen, Edel, Ohlendieck, Kay
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Blood Glucose - metabolism Diabetes Mellitus, Type 2 - metabolism Disease Models, Animal Electrophoresis, Gel, Two-Dimensional Humans Mass Spectrometry Molecular Sequence Data Muscle Proteins - chemistry Muscle Proteins - metabolism Muscle, Skeletal - chemistry Muscle, Skeletal - metabolism Obesity - metabolism Proteome - analysis Rats Rats, Inbred Strains Rats, Wistar
Online-Zugang:	Volltext
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