Malignant Potential of Colon Cancers in Relation to Cellular DNA and RNA Content

In order to evaluate the degree of malignancy of colon cancer, we attempted to measure the tumor cellular DNA and RNA content using FACS IV. The indices of DNA and RNA in cancer cells taken from surgical specimens were closely correlated with the grade of clinical staging and prognosis. In conclusio...

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Veröffentlicht in:Nippon Daicho Komonbyo Gakkai Zasshi 1988, Vol.41(2), pp.135-138
Hauptverfasser: Tomita, M., Shimoyama, T., Miyashita, K., Yamaoka, N., Yokota, M., Watabe, S., Ishikawa, H., Oh, S., Kawabuchi, T., Sato, T., Shiraishi, E., Furukawa, T., Miura, T.
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container_end_page 138
container_issue 2
container_start_page 135
container_title Nippon Daicho Komonbyo Gakkai Zasshi
container_volume 41
creator Tomita, M.
Shimoyama, T.
Miyashita, K.
Yamaoka, N.
Yokota, M.
Watabe, S.
Ishikawa, H.
Oh, S.
Kawabuchi, T.
Sato, T.
Shiraishi, E.
Furukawa, T.
Miura, T.
description In order to evaluate the degree of malignancy of colon cancer, we attempted to measure the tumor cellular DNA and RNA content using FACS IV. The indices of DNA and RNA in cancer cells taken from surgical specimens were closely correlated with the grade of clinical staging and prognosis. In conclusion, the measurement of DNA and RNA indices in colon cancer cells is valuable for the prediction of prognosis.
doi_str_mv 10.3862/jcoloproctology.41.135
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title Malignant Potential of Colon Cancers in Relation to Cellular DNA and RNA Content
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