Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats
Purpose: To evaluate wound healing in diabetic rats by using topic Andiroba oil (Carapa guianensis). Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba grou...
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Veröffentlicht in: | International archives of medicine 2017-10, Vol.10 |
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creator | Alves de Souza, Bruna Angelina Braga, Leandro Augusto Oliveira Lopes, Luiz Renato Ribeiro Júnior, Rubens Fernando Gonçalves Do Nascimento, Laiane Nazaré Silva Cavalcante, Lainy Carollyne da Costa Monteiro, Andrew Moraes Couteiro, Rodrigo Paracampo Yasojima, Edson Yuzur Hamoy, Moisés |
description | Purpose: To evaluate wound healing in diabetic rats by using topic Andiroba oil (Carapa guianensis).
Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba group (wound treatment with Andiroba oil). The wound was evaluated considering the macroscopic and microscopic parameters.
Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Andiroba oil and Collagenase in comparison to control group, especially after the 14th day. Morphometric data confirmed the structural findings.
Conclusion: There was significant effect in topical application of Andiroba oil on wound healing in rats with induced diabetes.
Keywords: Medicinal plants. Diabetes Mellitus. Wound healing. Rats. |
doi_str_mv | 10.3823/2533 |
format | Article |
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Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba group (wound treatment with Andiroba oil). The wound was evaluated considering the macroscopic and microscopic parameters.
Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Andiroba oil and Collagenase in comparison to control group, especially after the 14th day. Morphometric data confirmed the structural findings.
Conclusion: There was significant effect in topical application of Andiroba oil on wound healing in rats with induced diabetes.
Keywords: Medicinal plants. Diabetes Mellitus. Wound healing. Rats.</description><identifier>ISSN: 1755-7682</identifier><identifier>EISSN: 1755-7682</identifier><identifier>DOI: 10.3823/2533</identifier><language>eng</language><ispartof>International archives of medicine, 2017-10, Vol.10</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c643-a21938527e790c852223de1549f8b5c8f4eec52ea7d09dbe905a9e4d012f0b623</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Alves de Souza, Bruna Angelina</creatorcontrib><creatorcontrib>Braga, Leandro Augusto</creatorcontrib><creatorcontrib>Oliveira Lopes, Luiz Renato</creatorcontrib><creatorcontrib>Ribeiro Júnior, Rubens Fernando Gonçalves</creatorcontrib><creatorcontrib>Do Nascimento, Laiane Nazaré Silva</creatorcontrib><creatorcontrib>Cavalcante, Lainy Carollyne da Costa</creatorcontrib><creatorcontrib>Monteiro, Andrew Moraes</creatorcontrib><creatorcontrib>Couteiro, Rodrigo Paracampo</creatorcontrib><creatorcontrib>Yasojima, Edson Yuzur</creatorcontrib><creatorcontrib>Hamoy, Moisés</creatorcontrib><title>Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats</title><title>International archives of medicine</title><description>Purpose: To evaluate wound healing in diabetic rats by using topic Andiroba oil (Carapa guianensis).
Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba group (wound treatment with Andiroba oil). The wound was evaluated considering the macroscopic and microscopic parameters.
Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Andiroba oil and Collagenase in comparison to control group, especially after the 14th day. Morphometric data confirmed the structural findings.
Conclusion: There was significant effect in topical application of Andiroba oil on wound healing in rats with induced diabetes.
Keywords: Medicinal plants. Diabetes Mellitus. Wound healing. Rats.</description><issn>1755-7682</issn><issn>1755-7682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNpNkLtOwzAUQC1EJUrLP3hggCHgR5zYYxWVh1SJpZ2jG_u6GAW7slMBfw8VDEznTGc4hCw5u5NayHuhpDwjc94qVbWNFuf__IJclvLGWMN13czJbu092qnQ5OkqupDTADSFkd50kOEAdH8MEDGWUG5pivQjHaOjrwhjiHsaIoVxTJ8QKxdgwClYmmEqSzLzMBa8-uOCbB_W2-6p2rw8PnerTWWbWlYguJFaiRZbw-yPCCEdclUbrwdlta8RrRIIrWPGDWiYAoO1Y1x4NjRCLsj1b9bmVEpG3x9yeIf81XPWn070pxPyG-G0TzE</recordid><startdate>20171028</startdate><enddate>20171028</enddate><creator>Alves de Souza, Bruna Angelina</creator><creator>Braga, Leandro Augusto</creator><creator>Oliveira Lopes, Luiz Renato</creator><creator>Ribeiro Júnior, Rubens Fernando Gonçalves</creator><creator>Do Nascimento, Laiane Nazaré Silva</creator><creator>Cavalcante, Lainy Carollyne da Costa</creator><creator>Monteiro, Andrew Moraes</creator><creator>Couteiro, Rodrigo Paracampo</creator><creator>Yasojima, Edson Yuzur</creator><creator>Hamoy, Moisés</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20171028</creationdate><title>Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats</title><author>Alves de Souza, Bruna Angelina ; Braga, Leandro Augusto ; Oliveira Lopes, Luiz Renato ; Ribeiro Júnior, Rubens Fernando Gonçalves ; Do Nascimento, Laiane Nazaré Silva ; Cavalcante, Lainy Carollyne da Costa ; Monteiro, Andrew Moraes ; Couteiro, Rodrigo Paracampo ; Yasojima, Edson Yuzur ; Hamoy, Moisés</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c643-a21938527e790c852223de1549f8b5c8f4eec52ea7d09dbe905a9e4d012f0b623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Alves de Souza, Bruna Angelina</creatorcontrib><creatorcontrib>Braga, Leandro Augusto</creatorcontrib><creatorcontrib>Oliveira Lopes, Luiz Renato</creatorcontrib><creatorcontrib>Ribeiro Júnior, Rubens Fernando Gonçalves</creatorcontrib><creatorcontrib>Do Nascimento, Laiane Nazaré Silva</creatorcontrib><creatorcontrib>Cavalcante, Lainy Carollyne da Costa</creatorcontrib><creatorcontrib>Monteiro, Andrew Moraes</creatorcontrib><creatorcontrib>Couteiro, Rodrigo Paracampo</creatorcontrib><creatorcontrib>Yasojima, Edson Yuzur</creatorcontrib><creatorcontrib>Hamoy, Moisés</creatorcontrib><collection>CrossRef</collection><jtitle>International archives of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alves de Souza, Bruna Angelina</au><au>Braga, Leandro Augusto</au><au>Oliveira Lopes, Luiz Renato</au><au>Ribeiro Júnior, Rubens Fernando Gonçalves</au><au>Do Nascimento, Laiane Nazaré Silva</au><au>Cavalcante, Lainy Carollyne da Costa</au><au>Monteiro, Andrew Moraes</au><au>Couteiro, Rodrigo Paracampo</au><au>Yasojima, Edson Yuzur</au><au>Hamoy, Moisés</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats</atitle><jtitle>International archives of medicine</jtitle><date>2017-10-28</date><risdate>2017</risdate><volume>10</volume><issn>1755-7682</issn><eissn>1755-7682</eissn><abstract>Purpose: To evaluate wound healing in diabetic rats by using topic Andiroba oil (Carapa guianensis).
Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba group (wound treatment with Andiroba oil). The wound was evaluated considering the macroscopic and microscopic parameters.
Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Andiroba oil and Collagenase in comparison to control group, especially after the 14th day. Morphometric data confirmed the structural findings.
Conclusion: There was significant effect in topical application of Andiroba oil on wound healing in rats with induced diabetes.
Keywords: Medicinal plants. Diabetes Mellitus. Wound healing. Rats.</abstract><doi>10.3823/2533</doi></addata></record> |
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title | Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats |
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