Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats

Purpose: To evaluate wound healing in diabetic rats by using topic Andiroba oil (Carapa guianensis). Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba grou...

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Veröffentlicht in:International archives of medicine 2017-10, Vol.10
Hauptverfasser: Alves de Souza, Bruna Angelina, Braga, Leandro Augusto, Oliveira Lopes, Luiz Renato, Ribeiro Júnior, Rubens Fernando Gonçalves, Do Nascimento, Laiane Nazaré Silva, Cavalcante, Lainy Carollyne da Costa, Monteiro, Andrew Moraes, Couteiro, Rodrigo Paracampo, Yasojima, Edson Yuzur, Hamoy, Moisés
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container_title International archives of medicine
container_volume 10
creator Alves de Souza, Bruna Angelina
Braga, Leandro Augusto
Oliveira Lopes, Luiz Renato
Ribeiro Júnior, Rubens Fernando Gonçalves
Do Nascimento, Laiane Nazaré Silva
Cavalcante, Lainy Carollyne da Costa
Monteiro, Andrew Moraes
Couteiro, Rodrigo Paracampo
Yasojima, Edson Yuzur
Hamoy, Moisés
description Purpose: To evaluate wound healing in diabetic rats by using topic Andiroba oil (Carapa guianensis). Methods: Six male, adult, Wistar rats were distributed into three groups: Sham group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Andiroba group (wound treatment with Andiroba oil). The wound was evaluated considering the macroscopic and microscopic parameters. Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Andiroba oil and Collagenase in comparison to control group, especially after the 14th day. Morphometric data confirmed the structural findings. Conclusion: There was significant effect in topical application of Andiroba oil on wound healing in rats with induced diabetes.   Keywords: Medicinal plants. Diabetes Mellitus. Wound healing. Rats.
doi_str_mv 10.3823/2533
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title Effects of Andiroba oil (Carapa guianensis) on wound healing in alloxan-diabetic rats
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