Vestibular Meniere's Disease and Endolymphatic Hydrops

Vestibular Meniere's disease (VMD) is characterized by episodic vertigo without hearing loss or tinnitus. A comparative study was made in 44 patients with VMD in relation to duration of vertigo attacks, electrocochleographic findings and therapeutic effect of isosorbide (oral hyperosmotic agent...

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Veröffentlicht in:Equilibrium Research 1993, Vol.52(3), pp.332-338
Hauptverfasser: Takeda, Noriaki, Ashida, Kentaro, Taya, Naozo, Koizuka, Izumi, Sakagami, Masafumi, Doi, Katsumi, Ogino, Hitoshi, Matsunaga, Toru
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container_end_page 338
container_issue 3
container_start_page 332
container_title Equilibrium Research
container_volume 52
creator Takeda, Noriaki
Ashida, Kentaro
Taya, Naozo
Koizuka, Izumi
Sakagami, Masafumi
Doi, Katsumi
Ogino, Hitoshi
Matsunaga, Toru
description Vestibular Meniere's disease (VMD) is characterized by episodic vertigo without hearing loss or tinnitus. A comparative study was made in 44 patients with VMD in relation to duration of vertigo attacks, electrocochleographic findings and therapeutic effect of isosorbide (oral hyperosmotic agent). Isosorbide was effective in preventing attacks that persisted for more than 20 min in patients with a dominant-SP in electrocochleography. Six of these patiens subsequently developed typical Meniere's disease. These findings suggest that the pathogenesis of VMD with prolonged vertigo attacks is endolymphatic hydrops. However, isosorbide failed to prevent attacks that persisted for less than 20 min. It seems that the pathogenesis of VMD with short vertigo attacks is not endolymphatic hydrops.
doi_str_mv 10.3757/jser.52.332
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source J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese
subjects dominant-SP
electrocochleography
isosorbide
Meniere's disease
vestibular Meniere's disease
title Vestibular Meniere's Disease and Endolymphatic Hydrops
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